| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
disease | 0.400 | None | 0.985 | 66 | 0 | 1990 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.100 | None | 0.967 | 60 | 3 | 1991 | 2019 | ||||||||
|
sonic hedgehog signaling molecule | 0.461 | 0.846 | 0.98 |
|
disease | 0.100 | None | 0.982 | 56 | 0 | 2000 | 2019 | ||||||||
|
patched 1 | 0.398 | 0.885 | 1.00 |
|
disease | 0.400 | None | 1.000 | 48 | 2 | 1999 | 2020 | ||||||||
|
GLI family zinc finger 1 | 0.431 | 0.846 | 7.7E-14 |
|
disease | 0.100 | None | 1.000 | 27 | 0 | 2005 | 2019 | ||||||||
|
MYCN proto-oncogene, bHLH transcription factor | 0.454 | 0.808 | 0.89 |
|
disease | 0.400 | None | 0.960 | 25 | 1 | 1989 | 2019 | ||||||||
|
orthodenticle homeobox 2 | 0.514 | 0.808 | 0.92 |
|
disease | 0.400 | None | 1.000 | 25 | 0 | 1999 | 2019 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.400 | None | 0.960 | 25 | 0 | 2000 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.100 | None | 1.000 | 15 | 0 | 2005 | 2019 | ||||||||
|
signal transducer and activator of transcription 3 | 0.320 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 14 | 0 | 2008 | 2019 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.100 | None | 1.000 | 13 | 0 | 2002 | 2019 | ||||||||
|
SUFU negative regulator of hedgehog signaling | 0.493 | 0.769 | 1.00 |
|
disease | 0.400 | None | 1.000 | 12 | 0 | 2004 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 12 | 0 | 2005 | 2018 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | 0.319 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 12 | 0 | 2005 | 2018 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | 0.320 | 0.885 | 1.4E-06 |
|
disease | 0.400 | None | 1.000 | 12 | 0 | 2005 | 2018 | ||||||||
|
BMI1 proto-oncogene, polycomb ring finger | 0.448 | 0.808 | 0.94 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 2007 | 2019 | ||||||||
|
BCL2 apoptosis regulator | 0.291 | 0.885 | 0.56 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 1996 | 2019 | ||||||||
|
cyclin dependent kinase 6 | 0.471 | 0.731 | 0.98 |
|
disease | 0.380 | None | 1.000 | 10 | 0 | 2005 | 2018 | ||||||||
|
enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.376 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 2012 | 2020 | ||||||||
|
smoothened, frizzled class receptor | 0.489 | 0.731 | 4.3E-07 |
|
disease | 0.090 | None | 1.000 | 9 | 1 | 2000 | 2020 | ||||||||
|
atonal bHLH transcription factor 1 | 0.633 | 0.500 | 1.8E-02 |
|
disease | 0.390 | None | 1.000 | 9 | 0 | 2008 | 2019 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.380 | None | 1.000 | 9 | 0 | 1995 | 2020 | ||||||||
|
RE1 silencing transcription factor | 0.535 | 0.808 | 0.99 |
|
disease | 0.090 | None | 0.889 | 9 | 0 | 2000 | 2019 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.370 | None | 1.000 | 8 | 0 | 2001 | 2018 | ||||||||
|
prominin 1 | 0.410 | 0.846 | 1.9E-22 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 2009 | 2019 |