Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Integrative molecular concept modeling of prostate cancer progression. 17173048

2007
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice. 22581815

2012
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Therapeutic CTD_human Antiandrogen bicalutamide promotes tumor growth in a novel androgen-dependent prostate cancer xenograft model derived from a bicalutamide-treated patient. 16266977

2005
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Successful Treatment of Advanced Metastatic Prostate Cancer following Chemotherapy Based on Molecular Profiling. 22666205

2012
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer. 16421604

2006
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Cellular changes in prostate cancer cells induced by intermittent androgen suppression. 17141945

2007
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Therapeutic CTD_human Endocrine approaches in the therapy of prostate carcinoma. 15790600

2005
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations. 29295717

2018
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Microarray comparison of prostate tumor gene expression in African-American and Caucasian American males: a pilot project study. 19208208

2009
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Endocrine approaches in the therapy of prostate carcinoma. 15790600

2005
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Therapeutic CTD_human Successful Treatment of Advanced Metastatic Prostate Cancer following Chemotherapy Based on Molecular Profiling. 22666205

2012
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Therapeutic CTD_human Androgen deprivation therapy for prostate cancer: current status and future prospects. 15389811

2004
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Prostate tumors induced by the deletion of Apc have elevated levels of beta-catenin protein and are highly proliferative. 17363566

2007
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Niclosamide suppresses cell migration and invasion in enzalutamide resistant prostate cancer cells via Stat3-AR axis inhibition. 25970160

2015
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Therapeutic CTD_human Changing paradigms in management of metastatic Castration Resistant Prostate Cancer (mCRPC). 25062956

2014
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human The long tail of oncogenic drivers in prostate cancer. 29610475

2018
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Therapeutic CTD_human Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. 22610119

2012
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. 22610119

2012
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human The pace of prostatic intraepithelial neoplasia development is determined by the timing of Pten tumor suppressor gene excision. 19081794

2008
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Resveratrol and prostate cancer: promising role for microRNAs. 21714127

2011
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Therapeutic CTD_human Integrative molecular profiling of routine clinical prostate cancer specimens. 25735316

2015
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Genetic polymorphisms in IGF-I and IGFBP-3 are associated with prostate cancer in the Chinese population. 24586243

2014
Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Therapeutic CTD_human Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies. 25908785

2015
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. 19396168

2009
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.600 Biomarker CTD_human Integrative molecular concept modeling of prostate cancer progression. 17173048

2007