Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1316
Gene Symbol: KLF6
KLF6
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human

Entrez Id: 4601
Gene Symbol: MXI1
MXI1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.360 Biomarker CTD_human

Entrez Id: 8379
Gene Symbol: MAD1L1
MAD1L1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker CTD_human

Entrez Id: 2346
Gene Symbol: FOLH1
FOLH1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human 1alpha,25-Dihydroxyvitamin D3 down-regulates expression of prostate specific membrane antigen in prostate cancer cells. 18247401

2008

Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human 5alpha-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia. 17136762

2007

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Prostate tumors induced by the deletion of Apc have elevated levels of beta-catenin protein and are highly proliferative. 17363566

2007

Entrez Id: 857
Gene Symbol: CAV1
CAV1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human CAV-1 is located within the prostate cancer aggressiveness locus at 7q31-33, and was identified as being overexpressed in prostate tumors. 15948133

2005

Entrez Id: 463
Gene Symbol: ZFHX3
ZFHX3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.330 Biomarker CTD_human ATBF1 has been recently identified as a candidate prostate tumor suppressor gene. 16637072

2006

Entrez Id: 3925
Gene Symbol: STMN1
STMN1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.320 Biomarker CTD_human Stathmin levels increase early during normal mouse prostate development and again during prostate tumor development and progression. 17455228

2007

Entrez Id: 7113
Gene Symbol: TMPRSS2
TMPRSS2
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human TMPRSS2-ERG (T2E) structural rearrangements typify ∼50% of prostate tumors and result in overexpression of the ERG transcription factor. 28783165

2017

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human A gain of function TGFB1 polymorphism may be associated with late stage prostate cancer. 15159307

2004

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. 21946351

2011

Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.380 Biomarker CTD_human A prostate cancer susceptibility allele at 6q22 increases RFX6 expression by modulating HOXB13 chromatin binding. 24390282

2014

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes. 28319090

2017

Entrez Id: 56288
Gene Symbol: PARD3
PARD3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.310 Biomarker CTD_human A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes. 28319090

2017

Entrez Id: 51322
Gene Symbol: WAC
WAC
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker CTD_human A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes. 28319090

2017

Entrez Id: 11214
Gene Symbol: AKAP13
AKAP13
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker CTD_human A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes. 28319090

2017

Entrez Id: 26137
Gene Symbol: ZBTB20
ZBTB20
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker CTD_human A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes. 28319090

2017

Entrez Id: 10659
Gene Symbol: CELF2
CELF2
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.300 Biomarker CTD_human A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes. 28319090

2017

Entrez Id: 10481
Gene Symbol: HOXB13
HOXB13
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.380 Biomarker CTD_human A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer. 23104005

2012

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.600 Biomarker CTD_human Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. 19396168

2009

Entrez Id: 2078
Gene Symbol: ERG
ERG
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. 19396168

2009

Entrez Id: 10
Gene Symbol: NAT2
NAT2
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.330 Biomarker CTD_human Acetylation genotype and the genetic susceptibility to prostate cancer in a southern European population. 15717312

2005

Entrez Id: 5160
Gene Symbol: PDHA1
PDHA1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.310 Biomarker CTD_human Additionally, we found that PDHA1 and the PDC activator pyruvate dehydrogenase phosphatase 1 (PDP1) are frequently amplified and overexpressed at both the gene and protein levels in prostate tumors. 29335542

2018

Entrez Id: 54704
Gene Symbol: PDP1
PDP1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.310 Biomarker CTD_human Additionally, we found that PDHA1 and the PDC activator pyruvate dehydrogenase phosphatase 1 (PDP1) are frequently amplified and overexpressed at both the gene and protein levels in prostate tumors. 29335542

2018