Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 2016 2016
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.020 None 1.000 2 0 2003 2009
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 2014 2014
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None < 0.001 1 2 2014 2014
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 29126
Gene Symbol: CD274
CD274
CD274 molecule 0.324 0.923 1.9E-02
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 2018 2018
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.343 0.885 1.00
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 2010 2010
Entrez Id: 2260
Gene Symbol: FGFR1
FGFR1
fibroblast growth factor receptor 1 0.362 0.885 1.00
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.040 None 1.000 4 0 2007 2018
Entrez Id: 960
Gene Symbol: CD44
CD44
CD44 molecule (Indian blood group) 0.363 0.962 2.4E-07
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
nitric oxide synthase 2 0.364 0.923 4.0E-15
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 3815
Gene Symbol: KIT
KIT
KIT proto-oncogene, receptor tyrosine kinase 0.366 0.808 0.98
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.700 None 0.984 123 7 1998 2020
Entrez Id: 947
Gene Symbol: CD34
CD34
CD34 molecule 0.368 0.808 5.0E-06
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.050 None 1.000 5 0 2006 2018
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
interferon alpha 1 0.371 0.923
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 2011 2011
Entrez Id: 3447
Gene Symbol: IFNA13
IFNA13
interferon alpha 13 0.374 0.923
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 2011 2011
Entrez Id: 2056
Gene Symbol: EPO
EPO
erythropoietin 0.381 0.885 1.1E-02
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 1998 1998
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
heme oxygenase 1 0.381 0.923 9.7E-03
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.300 None 1.000 1 0 2007 2007
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
Janus kinase 2 0.385 0.885 0.65
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.050 None 1.000 5 1 2005 2014
Entrez Id: 3596
Gene Symbol: IL13
IL13
interleukin 13 0.386 0.846 1.4E-02
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.020 None 1.000 2 0 2009 2016
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
interleukin 2 receptor subunit alpha 0.389 0.885 5.5E-02
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.100 None 1.000 14 0 2003 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.390 0.808 0.49
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.020 None 1.000 2 0 2011 2015
Entrez Id: 4803
Gene Symbol: NGF
NGF
nerve growth factor 0.391 0.885 0.82
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 952
Gene Symbol: CD38
CD38
CD38 molecule 0.407 0.885 2.3E-06
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 1994 1994
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
nitric oxide synthase 1 0.408 0.885 1.00
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 811
Gene Symbol: CALR
CALR
calreticulin 0.413 0.923 0.89
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.010 None 1.000 1 0 2018 2018
Entrez Id: 3669
Gene Symbol: ISG20
ISG20
interferon stimulated exonuclease gene 20 0.414 0.846 2.9E-03
CUI: C0221013
Disease: Mastocytosis, Systemic
Mastocytosis, Systemic
disease 0.100 None 1.000 13 0 2003 2019