| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
2,4-dienoyl-CoA reductase 1 | 0.426 | 0.885 | 4.5E-14 |
|
disease | 0.010 | None | < 0.001 | 1 | 0 | 2010 | 2010 | ||||||||
|
5-hydroxytryptamine receptor 1F | 0.716 | 0.192 | 4.7E-03 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
5-hydroxytryptamine receptor 2A | 0.473 | 0.846 | 0.51 |
|
disease | 0.090 | None | 0.889 | 9 | 2 | 2001 | 2009 | ||||||||
|
5-hydroxytryptamine receptor 2C | 0.555 | 0.692 | 3.7E-02 |
|
disease | 0.040 | None | 1.000 | 4 | 1 | 2000 | 2012 | ||||||||
|
5-hydroxytryptamine receptor 3A | 0.608 | 0.538 | 1.7E-10 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2013 | 2013 | ||||||||
|
5-hydroxytryptamine receptor 6 | 0.626 | 0.500 | 1.9E-04 |
|
disease | 0.010 | None | 1.000 | 1 | 1 | 2002 | 2002 | ||||||||
|
adenosine A2a receptor | 0.526 | 0.769 | 0.60 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2005 | 2012 | ||||||||
|
adenosine A3 receptor | 0.682 | 0.500 | 1.4E-04 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2016 | 2016 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.020 | None | < 0.001 | 2 | 1 | 2008 | 2019 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2001 | 2006 | ||||||||
|
arrestin beta 2 | 0.561 | 0.769 | 0.51 |
|
disease | 0.010 | None | 1.000 | 1 | 1 | 2008 | 2008 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
BH3 interacting domain death agonist | 0.555 | 0.808 | 1.6E-11 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.060 | None | 0.500 | 6 | 3 | 2004 | 2014 | ||||||||
|
cannabinoid receptor 1 | 0.446 | 0.808 | 0.51 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||||||
|
catechol-O-methyltransferase | 0.400 | 0.923 | 1.1E-06 |
|
disease | 0.080 | None | 0.750 | 8 | 3 | 2003 | 2016 | ||||||||
|
cholinergic receptor muscarinic 1 | 0.653 | 0.577 | 0.99 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
cholinergic receptor muscarinic 2 | 0.585 | 0.615 | 0.18 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
coagulation factor II thrombin receptor | 0.444 | 0.846 | 8.5E-03 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
crystallin zeta | 0.524 | 0.731 | 5.7E-23 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2006 | 2006 | ||||||||
|
cytochrome P450 2D6 | 0.597 | 0.769 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2001 | 2002 | |||||||||
|
cytochrome P450 family 1 subfamily A member 2 | 0.494 | 0.923 | 2.5E-10 |
|
disease | 0.100 | None | 0.667 | 12 | 2 | 2000 | 2015 | ||||||||
|
cytochrome P450 family 17 subfamily A member 1 | 0.462 | 0.769 | 2.6E-04 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2014 | 2014 | ||||||||
|
cytochrome P450 family 2 subfamily B member 6 | 0.428 | 0.846 | 1.9E-10 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2004 | 2004 |