Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.100 None 0.920 25 4 2012 2020
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.100 None 1.000 13 0 2012 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
interleukin 17A 0.324 0.923 4.3E-02
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.040 None 1.000 4 0 2016 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.210 None 1.000 2 0 2005 2008
Entrez Id: 60
Gene Symbol: ACTB
ACTB
actin beta 0.325 0.923 0.99
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.100 None 1.000 10 2 1997 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.300 None 1.000 16 1 2008 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.600 None 0.914 152 6 1994 2019
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
mitogen-activated protein kinase 1 0.330 0.923 1.00
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.070 None 1.000 7 0 2004 2019
Entrez Id: 3565
Gene Symbol: IL4
IL4
interleukin 4 0.332 0.962 4.7E-03
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.030 None 1.000 3 1 2010 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.270 None 1.000 8 0 1997 2018
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
interleukin 1 alpha 0.333 0.962 1.6E-04
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.060 None 1.000 6 0 2004 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
major histocompatibility complex, class II, DR beta 1 0.333 0.923 1.1E-03
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.030 None 0.667 3 0 2008 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2
interleukin 2 0.336 0.885 0.48
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.010 None 1.000 1 0 2018 2018
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.100 None 0.967 30 3 1999 2019
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.100 None 0.929 28 2 1996 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.343 0.885 1.00
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.290 None 1.000 10 0 2013 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.345 0.923 0.66
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.200 None 1.000 1 0 2010 2010
Entrez Id: 3952
Gene Symbol: LEP
LEP
leptin 0.349 0.846 0.46
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.010 None 1.000 1 0 2011 2011
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
H3 histone pseudogene 10 0.350 0.846
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.020 None 1.000 2 0 2003 2017
Entrez Id: 836
Gene Symbol: CASP3
CASP3
caspase 3 0.351 0.923 0.10
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.230 None 1.000 6 0 2009 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR
vitamin D receptor 0.352 0.885 1.7E-05
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.100 None 1.000 16 0 2010 2019
Entrez Id: 4513
Gene Symbol: COX2
COX2
cytochrome c oxidase subunit II 0.352 0.962
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.010 None 1.000 1 0 2017 2017
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.230 None 1.000 3 0 2002 2012
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.600 None 1.000 42 0 2010 2020
Entrez Id: 1950
Gene Symbol: EGF
EGF
epidermal growth factor 0.357 0.923 8.5E-17
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.080 None 1.000 8 0 1997 2020