|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
GeneticVariation |
LHGDN |
Auto-antibodies, HLA and PTPN22: susceptibility markers for rheumatoid arthritis.
|
18156150 |
2008 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
Biomarker |
LHGDN |
Influence of HLA-DRB1 genes and the shared epitope on genetic susceptibility to rheumatoid arthritis in Taiwanese.
|
17309132 |
2007 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
GeneticVariation |
LHGDN |
HLA-DR/DQ haplotype in rheumatoid arthritis: novel allelic associations in UK Caucasians.
|
12233873 |
2002 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
GeneticVariation |
LHGDN |
Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus.
|
18309376 |
2008 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
GeneticVariation |
LHGDN |
Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci.
|
19116923 |
2009 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
GeneticVariation |
LHGDN |
HLA-DRB1 and persistent chronic inflammation contribute to cardiovascular events and cardiovascular mortality in patients with rheumatoid arthritis.
|
17266100 |
2007 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
Biomarker |
LHGDN |
The HLA-DRB1 shared epitope is not associated with antibodies against cyclic citrullinated peptide in Chinese patients with rheumatoid arthritis.
|
18465452 |
2008 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
Biomarker |
LHGDN |
The effect of HLA-DR on susceptibility to rheumatoid arthritis is influenced by the associated lymphotoxin alpha-tumor necrosis factor haplotype.
|
12528108 |
2003 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
Biomarker |
LHGDN |
Association of the HLA-DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritis.
|
18240242 |
2008 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
GeneticVariation |
LHGDN |
Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages.
|
14578453 |
2003 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
GeneticVariation |
LHGDN |
The association of HLA-DRB1 alleles with rheumatoid arthritis in the Chinese Shantou population: a follow-up study.
|
17534404 |
2007 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
GeneticVariation |
LHGDN |
Rheumatoid arthritis association in Colombian population is restricted to HLA-DRB1*04 QRRAA alleles.
|
11857065 |
2002 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
GeneticVariation |
LHGDN |
Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis.
|
17436241 |
2007 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
GeneticVariation |
LHGDN |
Molecular subtyping of HLA-DRB1*04 alleles in RA patients showed strongest association with highest relative risk with DRB1*0404.
|
12793199 |
2003 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
Biomarker |
LHGDN |
Protective effect of noninherited maternal HLA-DR antigens on rheumatoid arthritis development.
|
18077428 |
2007 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
Biomarker |
LHGDN |
Role of human leukocyte antigen DRB1*0307 and DRB1*0308 in susceptibility to juvenile rheumatoid arthritis.
|
12846065 |
2003 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
GeneticVariation |
LHGDN |
HLA-DRB1*0404 is strongly associated with high titers of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis.
|
18799094 |
2009 |
|
HLA-DRB1
|
Rheumatoid Arthritis
|
0.500 |
GeneticVariation |
LHGDN |
Prevalence of DRB1*01 and DRB1*04 alleles in a group of patients with rheumatoid arthritis living in Liguria.
|
16366416 |
2005 |
|
HLA-DRB1
|
Asthma
|
0.500 |
GeneticVariation |
LHGDN |
HLA-DRB1 alleles did not predict the presence of asthma, but multi-allelic tests of association showed the locus accounted for approximately 33% of the variance of the total serum IgE concentration and 17% of the variance of the specific IgE titres to HDM.
|
12620968 |
2003 |
|
HLA-DRB1
|
Ulcerative Colitis
|
0.500 |
Biomarker |
LHGDN |
The allele frequency of HLA-DRB1*09 was significantly higher in patients with UC diagnosed at the age of 40 years or older than in those with UC diagnosed before the age of 40 years (OR=2.31, Pc=0.022).
|
18416774 |
2008 |
|
HLA-DRB1
|
Diabetes Mellitus, Insulin-Dependent
|
0.500 |
GeneticVariation |
LHGDN |
D6S265*15 marks a DRB1*15, DQB1*0602 haplotype associated with attenuated protection from type 1 diabetes mellitus.
|
16320082 |
2005 |
|
HLA-DRB1
|
Diabetes Mellitus, Insulin-Dependent
|
0.500 |
GeneticVariation |
LHGDN |
We discovered that younger individuals with HLA-DRB1*0301/DRB1*04 and INS I/I genotypes exhibited increased susceptibility to T1DM, whereas the interaction of INS I/I and CTLA4 G/G genotypes was more common in older children with T1DM.
|
16390390 |
2005 |
|
HLA-DRB1
|
Diabetes Mellitus, Insulin-Dependent
|
0.500 |
Biomarker |
LHGDN |
We found an increased frequency of HLA-DRB1*08 and a decreased frequency of HLA-DRB1*04 in the group with T2DM vs. T1DM [p = 0.0001, odds ratio (OR) = 10.58, 95% confidence interval (CI) = 3-40.8 and p = 0.0006, OR = 0.24, 95% CI = 0.11-0.53, respectively].
|
17341285 |
2007 |
|
HLA-DRB1
|
Diabetes Mellitus, Insulin-Dependent
|
0.500 |
GeneticVariation |
LHGDN |
HLA-DRB1 (*)04 and HLA-DQB1 (*)0302 have been detected as risk factors for T1DM in adults and particularly in children (P<0.0001, OR=22.9 and 46.5 respectively).
|
17318773 |
2007 |
|
HLA-DRB1
|
Diabetes Mellitus, Insulin-Dependent
|
0.500 |
GeneticVariation |
LHGDN |
In addition to HLA-DRB1*15 and DQB1*0602 alleles, DRB1*11, DRB1*13, and DQA1*01 allele groups were associated with protection against the development of type 1 diabetes in Brazilian patients.
|
12021129 |
2002 |