×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Genotype-phenotype relationship in Brugada syndrome: electrocardiographic features differentiate SCN5A-related patients from non-SCN5A-related patients.
12106943 2002
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
We screened patients with SUNDS for mutations in SCN5A , the gene known to cause Brugada syndrome , as well as genes encoding ion channels associated with the long-QT syndrome.
11823453 2002
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Natural history of Brugada syndrome: insights for risk stratification and management.
11901046 2002
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
Genotype-phenotype relationship in Brugada syndrome: electrocardiographic features differentiate SCN5A-related patients from non-SCN5A-related patients.
12106943 2002
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Clinical, genetic, and biophysical characterization of SCN5A mutations associated with atrioventricular conduction block.
11804990 2002
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
Nucleotide changes in the translated region of SCN5A from Japanese patients with Brugada syndrome and control subjects.
12639704 2003
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
The implications of genetic mutations in the sodium channel gene (SCN5A).
14753626 2003
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Congenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A).
14523039 2003
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Novel brugada SCN5A mutation leading to ST segment elevation in the inferior or the right precordial leads.
12693506 2003
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
A cardiac sodium channel mutation cosegregates with a rare connexin40 genotype in familial atrial standstill.
12522116 2003
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
A novel LQT3 mutation implicates the human cardiac sodium channel domain IVS6 in inactivation kinetics.
12650885 2003
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
Mutations in the cardiac sodium channel gene SCN5A are only known to cause BS .
14961552 2003
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
Catecholamine-provoked microvoltage T wave alternans in genotyped long QT syndrome.
12877697 2003
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
The use of genotype-phenotype correlations in mutation analysis for the long QT syndrome.
12566525 2003
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Mutations in the cardiac sodium channel gene SCN5A are only known to cause BS .
14961552 2003
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
Novel pore mutation in SCN5A manifests as a spectrum of phenotypes ranging from atrial flutter, conduction disease, and Brugada syndrome to sudden cardiac death.
15851228 2004
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
In families with Brugada syndrome , the data suggest that ajmaline testing is valuable in the diagnosis of SCN5A carriers.
15520322 2004
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
A trafficking defective, Brugada syndrome-causing SCN5A mutation rescued by drugs.
15023552 2004
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
In this study, three novel mutations on the SCN5A gene were identified and characterized in different patients with Brugada syndrome .
15057319 2004
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
Structural effects of an LQT-3 mutation on heart Na+ channel gating.
14990510 2004
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
Sodium channel mutations and susceptibility to heart failure and atrial fibrillation.
15671429 2005
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
Substitution of a conserved alanine in the domain IIIS4-S5 linker of the cardiac sodium channel causes long QT syndrome.
16039271 2005
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
GeneticVariation
CLINVAR
High risk for bradyarrhythmic complications in patients with Brugada syndrome caused by SCN5A gene mutations.
16325048 2005
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
Gene sequencing in neonates and infants with the long QT syndrome.
16379539 2005
×
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
Brugada Syndrome (disorder)
1.000
CausalMutation
CLINVAR
Compendium of cardiac channel mutations in 541 consecutive unrelated patients referred for long QT syndrome genetic testing.
15840476 2005