| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
membrane metalloendopeptidase | 0.407 | 0.808 | 1.5E-18 |
|
disease | 0.300 | None | 0.955 | 89 | 5 | 2001 | 2020 | ||||||||
|
insulin degrading enzyme | 0.604 | 0.577 | 6.6E-03 |
|
disease | 0.600 | None | 0.955 | 88 | 9 | 2000 | 2019 | ||||||||
|
alkylglycerone phosphate synthase | 0.670 | 0.538 | 1.00 |
|
disease | 0.100 | None | 1.000 | 84 | 0 | 1999 | 2020 | ||||||||
|
TAR DNA binding protein | 0.493 | 0.808 | 0.99 |
|
disease | 0.100 | None | 0.976 | 83 | 1 | 2008 | 2020 | ||||||||
|
cyclin dependent kinase 5 | 0.495 | 0.846 | 0.14 |
|
disease | 0.300 | None | 1.000 | 77 | 1 | 2000 | 2020 | ||||||||
|
phosphatidylinositol binding clathrin assembly protein | 0.592 | 0.538 | 1.00 |
|
disease | 0.500 | None | 0.947 | 75 | 19 | 2009 | 2019 | ||||||||
|
ADAM metallopeptidase domain 10 | 0.489 | 0.846 | 1.00 |
|
disease | 0.700 | None | 0.986 | 74 | 8 | 2000 | 2019 | ||||||||
|
serpin family A member 3 | 0.486 | 0.846 | 8.8E-14 |
|
disease | 0.100 | None | 0.926 | 68 | 2 | 1988 | 2019 | ||||||||
|
single-strand-selective monofunctional uracil-DNA glycosylase 1 | 0.322 | 0.923 | 4.5E-04 |
|
disease | 0.100 | None | 0.985 | 67 | 0 | 2017 | 2020 | ||||||||
|
granulin precursor | 0.435 | 0.846 | 7.0E-02 |
|
disease | 0.200 | None | 0.970 | 66 | 8 | 2006 | 2019 | ||||||||
|
ATP binding cassette subfamily A member 7 | 0.644 | 0.577 | 2.1E-55 |
|
disease | 0.500 | None | 0.985 | 65 | 13 | 2011 | 2019 | ||||||||
|
interleukin 1 alpha | 0.333 | 0.962 | 1.6E-04 |
|
disease | 0.100 | None | 0.885 | 61 | 1 | 1989 | 2019 | ||||||||
|
glial fibrillary acidic protein | 0.421 | 0.885 | 1.5E-06 |
|
disease | 0.100 | None | 0.949 | 59 | 0 | 1987 | 2020 | ||||||||
|
superoxide dismutase 1 | 0.379 | 0.962 | 0.18 |
|
disease | 0.300 | None | 0.982 | 57 | 5 | 1989 | 2020 | ||||||||
|
neurofilament light | 0.488 | 0.769 |
|
disease | 0.100 | None | 0.982 | 56 | 0 | 1990 | 2020 | |||||||||
|
choline O-acetyltransferase | 0.520 | 0.808 | 5.6E-11 |
|
disease | 0.300 | None | 0.981 | 54 | 11 | 1987 | 2019 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.400 | None | 0.944 | 54 | 5 | 1999 | 2019 | ||||||||
|
peroxisome proliferator activated receptor gamma | 0.358 | 0.885 | 2.9E-02 |
|
disease | 0.400 | None | 0.907 | 54 | 6 | 2000 | 2019 | ||||||||
|
cathepsin D | 0.478 | 0.846 | 9.2E-04 |
|
disease | 0.100 | None | 0.887 | 53 | 3 | 1991 | 2020 | ||||||||
|
sirtuin 1 | 0.378 | 0.885 | 8.7E-02 |
|
disease | 0.100 | None | 0.981 | 53 | 0 | 2005 | 2020 | ||||||||
|
ATP binding cassette subfamily A member 1 | 0.467 | 0.846 | 1.5E-13 |
|
disease | 0.200 | None | 0.904 | 52 | 13 | 2003 | 2020 | ||||||||
|
nuclear factor, erythroid 2 like 2 | 0.357 | 0.885 | 3.6E-03 |
|
disease | 0.300 | None | 0.981 | 52 | 0 | 2008 | 2020 | ||||||||
|
bridging integrator 1 | 0.550 | 0.692 | 0.78 |
|
disease | 0.500 | None | 0.980 | 51 | 7 | 2011 | 2020 | ||||||||
|
islet amyloid polypeptide | 0.507 | 0.808 | 3.2E-03 |
|
disease | 0.100 | None | 1.000 | 50 | 1 | 2006 | 2019 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.300 | None | 0.960 | 50 | 2 | 1997 | 2019 |