Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.450 Biomarker CTD_human Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray. 16367923

2006

Entrez Id: 10395
Gene Symbol: DLC1
DLC1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.410 Therapeutic CTD_human Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer. 26401016

2015

Entrez Id: 8314
Gene Symbol: BAP1
BAP1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Germline BAP1 Mutational Landscape of Asbestos-Exposed Malignant Mesothelioma Patients with Family History of Cancer. 26719535

2016

Entrez Id: 8314
Gene Symbol: BAP1
BAP1
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Inference on germline BAP1 mutations and asbestos exposure from the analysis of familial and sporadic mesothelioma in a high-risk area. 25231345

2015

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Expression of AFP and STAT3 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in AFP-producing gastric cancer cells. 23382965

2013

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human A genetic variant in 3'-untranslated region of cyclooxygenases-2 gene is associated with risk of gastric cancer in a Chinese population. 22385256

2012

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Capsaicin consumption, Helicobacter pylori CagA status and IL1B-31C>T genotypes: a host and environment interaction in gastric cancer. 22414649

2012

Entrez Id: 1019
Gene Symbol: CDK4
CDK4
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Cyclin D1/cdk4, estrogen receptors α and β, in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat gastric carcinogenesis: immunohistochemical study. 21628965

2011

Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human DNA repair gene and MTHFR gene polymorphisms as prognostic markers in locally advanced adenocarcinoma of the esophagus or stomach treated with cisplatin and 5-fluorouracil-based neoadjuvant chemotherapy. 21347786

2011

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human 15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer. 19584167

2009

Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Genetic susceptibility to cancer: the role of polymorphisms in candidate genes. 18505952

2008

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells. 17003101

2007

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Effect of celecoxib on E-cadherin, VEGF, Microvessel density and apoptosis in gastric cancer. 17224647

2007

Entrez Id: 864
Gene Symbol: RUNX3
RUNX3
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray. 16367923

2006

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Implication of peroxisome proliferator-activated receptor gamma and proinflammatory cytokines in gastric carcinogenesis: link to Helicobacter pylori-infection. 15492468

2004

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.400 Biomarker CTD_human Overexpression of cyclooxygenase-2 protein is less frequent in gastric cancers with microsatellite instability. 10404093

1999

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.390 Therapeutic CTD_human Three-gene predictor of clinical outcome for gastric cancer patients treated with chemotherapy. 21173787

2012

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.390 Biomarker CTD_human Three-gene predictor of clinical outcome for gastric cancer patients treated with chemotherapy. 21173787

2012

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.390 Biomarker CTD_human MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib. 22042947

2011

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.390 Therapeutic CTD_human MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib. 22042947

2011

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.390 Biomarker CTD_human "Gefitinib (""Iressa"", ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells." 15723263

2005

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.390 Therapeutic CTD_human "Gefitinib (""Iressa"", ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells." 15723263

2005

Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 Biomarker CTD_human Efficacy of laser capture microdissection plus RT-PCR technique in analyzing gene expression levels in human gastric cancer and colon cancer. 18652704

2008

Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 Biomarker CTD_human Thymidylate synthase, dihydropyrimidine dehydrogenase, orotate phosphoribosyltransferase mRNA and protein expression levels in solid tumors in large scale population analysis. 19020767

2008

Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms
0.370 Biomarker CTD_human Modified FOLFOX-6 chemotherapy in advanced gastric cancer: Results of phase II study and comprehensive analysis of polymorphisms as a predictive and prognostic marker. 18505590

2008