Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
O-6-methylguanine-DNA methyltransferase 0.412 0.885 1.2E-07
Secondary malignant neoplasm of colon and/or rectum
disease 0.100 None 1.000 10 0 2010 2020
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit 0.445 0.846 1.6E-07
Secondary malignant neoplasm of colon and/or rectum
disease 0.090 None 1.000 9 0 2005 2019
Entrez Id: 7167
Gene Symbol: TPI1
TPI1
triosephosphate isomerase 1 0.517 0.846 3.0E-02
Secondary malignant neoplasm of colon and/or rectum
disease 0.090 None 1.000 9 0 2018 2020
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
Raf-1 proto-oncogene, serine/threonine kinase 0.418 0.885 0.85
Secondary malignant neoplasm of colon and/or rectum
disease 0.080 None 1.000 8 0 2009 2019
Entrez Id: 2984
Gene Symbol: GUCY2C
GUCY2C
guanylate cyclase 2C 0.599 0.577 1.4E-30
Secondary malignant neoplasm of colon and/or rectum
disease 0.080 None 1.000 8 0 1998 2018
Entrez Id: 22882
Gene Symbol: ZHX2
ZHX2
zinc fingers and homeoboxes 2 0.510 0.654 3.4E-02
Secondary malignant neoplasm of colon and/or rectum
disease 0.080 None 1.000 8 0 2009 2019
Entrez Id: 407035
Gene Symbol: MIR31
MIR31
microRNA 31 0.471 0.769
Secondary malignant neoplasm of colon and/or rectum
disease 0.080 None 0.875 8 0 2014 2020
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7
mitogen-activated protein kinase kinase 7 0.419 0.808 1.00
Secondary malignant neoplasm of colon and/or rectum
disease 0.080 None 1.000 8 0 2013 2019
Entrez Id: 29126
Gene Symbol: CD274
CD274
CD274 molecule 0.324 0.923 1.9E-02
Secondary malignant neoplasm of colon and/or rectum
disease 0.070 None 1.000 7 0 2017 2019
Entrez Id: 1806
Gene Symbol: DPYD
DPYD
dihydropyrimidine dehydrogenase 0.493 0.846 3.4E-22
Secondary malignant neoplasm of colon and/or rectum
disease 0.070 None 1.000 7 0 2003 2019
Entrez Id: 4233
Gene Symbol: MET
MET
MET proto-oncogene, receptor tyrosine kinase 0.380 0.846 0.97
Secondary malignant neoplasm of colon and/or rectum
disease 0.070 None 1.000 7 0 2011 2019
Entrez Id: 3791
Gene Symbol: KDR
KDR
kinase insert domain receptor 0.378 0.885 1.00
Secondary malignant neoplasm of colon and/or rectum
disease 0.070 None 1.000 7 0 2013 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
single-strand-selective monofunctional uracil-DNA glycosylase 1 0.322 0.923 4.5E-04
Secondary malignant neoplasm of colon and/or rectum
disease 0.070 None 1.000 7 0 2017 2019
Entrez Id: 7361
Gene Symbol: UGT1A
UGT1A
UDP glucuronosyltransferase family 1 member A complex locus 0.540 0.654
Secondary malignant neoplasm of colon and/or rectum
disease 0.060 None 1.000 6 0 2011 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
Secondary malignant neoplasm of colon and/or rectum
disease 0.060 None 0.833 6 1 2003 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
Secondary malignant neoplasm of colon and/or rectum
disease 0.050 None 1.000 5 0 2009 2019
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
TIMP metallopeptidase inhibitor 1 0.380 0.885 0.50
Secondary malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2007 2019
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
erb-b2 receptor tyrosine kinase 3 0.448 0.808 1.7E-15
Secondary malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2015 2019
Entrez Id: 54577
Gene Symbol: UGT1A7
UGT1A7
UDP glucuronosyltransferase family 1 member A7 0.550 0.692 8.7E-14
Secondary malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 2 2008 2017
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.318 0.885 0.27
Secondary malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2012 2017
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
mannose receptor C-type 1 0.413 0.846 0.94
Secondary malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2011 2019
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
insulin like growth factor 1 receptor 0.399 0.885 0.97
Secondary malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2008 2017
Entrez Id: 7150
Gene Symbol: TOP1
TOP1
DNA topoisomerase I 0.542 0.692 1.00
Secondary malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2012 2017
Entrez Id: 23542
Gene Symbol: MAPK8IP2
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2 0.628 0.654 1.00
Secondary malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2014 2018
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
ATP binding cassette subfamily G member 2 (Junior blood group) 0.419 0.885 2.1E-32
Secondary malignant neoplasm of colon and/or rectum
disease 0.040 None 1.000 4 0 2013 2015