Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
Secondary malignant neoplasm of colon and/or rectum
0.040 Biomarker BEFREE We assessed 44 gene polymorphisms in 16 genes (TYMS, MTHFR, GSTP1, GSTM1, GSTT1, DPYD, XRCC1, XRCC3, XPD, ERCC1, RECQ1, RAD54L, ABCB1, ABCC2, ABCG2 and UGT2B7) in 64 patients with metastatic colorectal cancer (CRC) receiving capecitabine/oxaliplatin and 76 patients with advanced gastroesophageal cancer (GEC) receiving epirubicin/cisplatin/capecitabine, respectively. 25677447

2015

Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
Secondary malignant neoplasm of colon and/or rectum
0.040 Biomarker BEFREE Combination of SNPs with MTHFR and ABCG2 may play a role in helping clinicians to select first-line chemotherapy for patients with metastatic colorectal cancer. 24338217

2014

Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
Secondary malignant neoplasm of colon and/or rectum
0.040 Biomarker BEFREE Using immunohistochemistry (IHC), we evaluated the biological role of CES2 and the expression of breast cancer resistance protein (BCRP/ABCG2) in 58 consecutive mCRC patients, who had undergone a first-line CPT-11/5-FU/leucovirin (FOLFIRI) regimen. 25198900

2014

Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
Secondary malignant neoplasm of colon and/or rectum
0.040 AlteredExpression BEFREE Expression of ABCG2 associated with tumor response in metastatic colorectal cancer patients receiving first-line FOLFOX therapy--preliminary evidence. 23558935

2013