×
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
Kidney Failure, Chronic
0.300
SusceptibilityMutation
RGD
Role of Nitric Oxide Pathway in Development and Progression of Chronic Kidney Disease in Rats Sensitive and Resistant to its Occurrence in an Experimental Model of 5/6 Nephrectomy.
29018182 2017
×
Entrez Id: 6569
Gene Symbol: SLC34A1
SLC34A1
Kidney Failure, Chronic
0.300
Biomarker
RGD
The pathophysiology of early-stage chronic kidney disease-mineral bone disorder (CKD-MBD) and response to phosphate binders in the rat.
21826734 2011
×
Entrez Id: 6569
Gene Symbol: SLC34A1
SLC34A1
Kidney Failure, Chronic
0.300
Biomarker
RGD
Regulation of NaPi-IIa mRNA and transporter protein in chronic renal failure: role of parathyroid hormone (PTH) and dietary phosphate (Pi).
15452708 2004
×
Entrez Id: 9365
Gene Symbol: KL
KL
Kidney Failure, Chronic
0.300
Biomarker
RGD
This is the first report showing the expression of the klotho gene in the kidney is regulated under sustained circulatory stress such as long-term hypertension, diabetes mellitus, and chronic renal failure .
9731228 1998
×
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
Kidney Failure, Chronic
0.300
Biomarker
RGD
Urine levels of NOx and the expression of glomerular eNOS and tubulointerstitial nNOS were significantly decreased in CRF rats compared with normal rats.
18089446 2008
×
Entrez Id: 23560
Gene Symbol: GTPBP4
GTPBP4
Kidney Failure, Chronic
0.300
Biomarker
RGD
Identification of a novel nuclear guanosine triphosphate-binding protein differentially expressed in renal disease.
11316846 2001
×
Entrez Id: 9365
Gene Symbol: KL
KL
Kidney Failure, Chronic
0.300
Biomarker
RGD
Recent studies have shown that expression of renal klotho gene is regulated in animal models of metabolic diseases and in humans with chronic renal failure .
11967236 2002
×
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Kidney Failure, Chronic
0.280
Biomarker
RGD
Protective role of quercetin against lead-induced inflammatory response in rat kidney through the ROS-mediated MAPKs and NF-κB pathway.
22728154 2012
×
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Kidney Failure, Chronic
0.280
Biomarker
RGD
Curcumin and enalapril ameliorate renal failure by antagonizing inflammation in 5/6 nephrectomized rats: role of phospholipase and cyclooxygenase.
22031851 2012
×
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Kidney Failure, Chronic
0.280
Biomarker
RGD
CRF rats showed increased plasma IL-1 alpha, IL1-beta , IL-6, TNF-alpha, and sICAM-1 levels and decreased anti-inflammatory cytokines IL-4 and 10 levels, hypertension, and dyslipidemia.20199183 2010
×
Entrez Id: 1234
Gene Symbol: CCR5
CCR5
Kidney Failure, Chronic
0.260
Biomarker
RGD
Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats.
19535570 2009
×
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
Kidney Failure, Chronic
0.250
Biomarker
RGD
Renal endothelin gene expression is increased in remnant kidney and correlates with disease progression.
8441230 1993
×
Entrez Id: 26762
Gene Symbol: HAVCR1
HAVCR1
Kidney Failure, Chronic
0.240
Biomarker
RGD
Structural equation modeling highlights the potential of Kim-1 as a biomarker for chronic kidney disease.
22269876 2012
×
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Kidney Failure, Chronic
0.230
Therapeutic
RGD
Curcumin alleviates oxidative stress, inflammation, and renal fibrosis in remnant kidney through the Nrf2-keap1 pathway.
23174956 2013
×
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
Kidney Failure, Chronic
0.230
Therapeutic
RGD
[Effects of shenshuai II recipe on the protein expressions of Ang II and nNOS in chronic renal failure rats' nephridial tissue].
23185775 2012
×
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
Kidney Failure, Chronic
0.230
Biomarker
RGD
Vitamin E reduces glomerulosclerosis, restores renal neuronal NOS, and suppresses oxidative stress in the 5/6 nephrectomized rat.
17200156 2007
×
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
Kidney Failure, Chronic
0.230
Therapeutic
RGD
Delayed mTOR inhibition with low dose of everolimus reduces TGFβ expression, attenuates proteinuria and renal damage in the renal mass reduction model.
22427849 2012
×
Entrez Id: 3240
Gene Symbol: HP
HP
Kidney Failure, Chronic
0.230
Biomarker
RGD
Influence of different stages of experimental chronic kidney disease on rats locomotor and postural skeletal muscles microcirculation.
18569920 2008
×
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
Kidney Failure, Chronic
0.220
Biomarker
RGD
High-calorie diet with moderate protein restriction prevents cachexia and ameliorates oxidative stress, inflammation and proteinuria in experimental chronic kidney disease.
20820841 2010
×
Entrez Id: 3931
Gene Symbol: LCAT
LCAT
Kidney Failure, Chronic
0.220
Biomarker
RGD
ACAT inhibition reverses LCAT deficiency and improves plasma HDL in chronic renal failure.
15280162 2004
×
Entrez Id: 596
Gene Symbol: BCL2
BCL2
Kidney Failure, Chronic
0.220
Therapeutic
RGD
Epoetin delta as an antifibrotic agent in the remnant kidney rat: a possible role for transforming growth factor beta and hepatocyte growth factor.
20424483 2010
×
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
Kidney Failure, Chronic
0.220
Biomarker
RGD
Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats.
19535570 2009
×
Entrez Id: 2057
Gene Symbol: EPOR
EPOR
Kidney Failure, Chronic
0.220
Biomarker
RGD
Down-Regulation of Cardiac Erythropoietin Receptor and its Downstream Activated Signal Transducer Phospho-STAT-5 in a Rat Model of Chronic Kidney Disease.
27468524 2016
×
Entrez Id: 632
Gene Symbol: BGLAP
BGLAP
Kidney Failure, Chronic
0.210
Biomarker
RGD
Serum osteocalcin and to a lesser extend tartrate-resistant acid phosphatase and urinary pyridinoline and deoxypyridinoline crosslinks were higher in the CRF animals compared to the shams, particularly in the animals of the HPD group with more pronounced CRF .
17365904 2007
×
Entrez Id: 1191
Gene Symbol: CLU
CLU
Kidney Failure, Chronic
0.210
Biomarker
RGD
Urinary biomarkers track the progression of nephropathy in hypertensive and obese rats.
24325231 2014