Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
toll like receptor 4 0.321 0.962 4.6E-09
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 0.947 19 2 2003 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
NLR family pyrin domain containing 3 0.361 0.962 8.1E-04
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.400 None 1.000 18 1 2010 2019
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
interleukin 1 receptor antagonist 0.373 0.923 3.1E-02
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.400 None 0.722 18 1 1997 2015
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
major histocompatibility complex, class I, B 0.379 0.885 3.9E-05
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.200 None 1.000 17 6 1979 2019
Entrez Id: 4261
Gene Symbol: CIITA
CIITA
class II major histocompatibility complex transactivator 0.536 0.808 1.4E-07
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 0.882 17 2 2001 2015
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 1.000 15 0 2009 2020
Entrez Id: 5788
Gene Symbol: PTPRC
PTPRC
protein tyrosine phosphatase receptor type C 0.435 0.808 1.00
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 0.867 15 2 2000 2009
Entrez Id: 6352
Gene Symbol: CCL5
CCL5
C-C motif chemokine ligand 5 0.403 0.885 1.8E-03
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 0.933 15 0 1997 2018
Entrez Id: 100133941
Gene Symbol: CD24
CD24
CD24 molecule 0.472 0.769
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 0.929 14 1 2003 2016
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
chitinase 3 like 1 0.419 0.885 1.1E-05
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 1.000 14 1 2010 2019
Entrez Id: 1410
Gene Symbol: CRYAB
CRYAB
crystallin alpha B 0.515 0.731 2.2E-02
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 1.000 14 0 1996 2019
Entrez Id: 2670
Gene Symbol: GFAP
GFAP
glial fibrillary acidic protein 0.421 0.885 1.5E-06
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 1.000 14 0 1997 2020
Entrez Id: 355
Gene Symbol: FAS
FAS
Fas cell surface death receptor 0.372 0.923 0.81
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 0.929 14 1 1998 2020
Entrez Id: 406947
Gene Symbol: MIR155
MIR155
microRNA 155 0.384 0.885
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 1.000 14 1 2011 2019
Entrez Id: 50616
Gene Symbol: IL22
IL22
interleukin 22 0.393 0.885 1.9E-04
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 1.000 14 0 2009 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.200 None 1.000 14 4 2004 2020
Entrez Id: 706
Gene Symbol: TSPO
TSPO
translocator protein 0.444 0.885 2.7E-04
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 1.000 14 1 2013 2019
Entrez Id: 8163
Gene Symbol: CDR3
CDR3
Cerebellar degeneration-related autoantigen-3 0.472 0.808
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 1.000 14 0 1993 2019
Entrez Id: 10673
Gene Symbol: TNFSF13B
TNFSF13B
TNF superfamily member 13b 0.460 0.731 0.98
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 1.000 13 0 2008 2018
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
intercellular adhesion molecule 1 0.364 0.962 3.5E-02
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.400 None 0.846 13 2 1994 2019
Entrez Id: 959
Gene Symbol: CD40LG
CD40LG
CD40 ligand 0.414 0.846 0.72
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 0.923 13 0 2000 2019
Entrez Id: 1154
Gene Symbol: CISH
CISH
cytokine inducible SH2 containing protein 0.500 0.808 5.4E-04
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 1.000 12 0 2012 2019
Entrez Id: 2669
Gene Symbol: GEM
GEM
GTP binding protein overexpressed in skeletal muscle 0.467 0.769 1.2E-08
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 0.833 12 0 2005 2019
Entrez Id: 3107
Gene Symbol: HLA-C
HLA-C
major histocompatibility complex, class I, C 0.415 0.846 1.6E-06
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 1.000 12 0 1995 2017
Entrez Id: 3952
Gene Symbol: LEP
LEP
leptin 0.349 0.846 0.46
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis
disease 0.100 None 0.917 12 0 2005 2020