| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 1.000 | None | 0.982 | 417 | 9 | 1953 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.100 | None | 0.939 | 49 | 1 | 1992 | 2019 | ||||||||
|
alpha fetoprotein | 0.429 | 0.885 | 1.1E-11 |
|
disease | 0.100 | None | 0.944 | 18 | 0 | 1980 | 2019 | ||||||||
|
checkpoint kinase 1 | 0.492 | 0.808 | 3.1E-08 |
|
disease | 0.100 | None | 1.000 | 15 | 0 | 1999 | 2020 | ||||||||
|
H2A.X variant histone | 0.484 | 0.808 | 0.18 |
|
disease | 0.100 | None | 1.000 | 14 | 0 | 2004 | 2019 | ||||||||
|
nibrin | 0.467 | 0.808 | 2.2E-16 |
|
disease | 0.100 | None | 1.000 | 13 | 0 | 1997 | 2011 | ||||||||
|
aprataxin | 0.590 | 0.500 | 4.0E-10 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 2000 | 2017 | ||||||||
|
ATR serine/threonine kinase | 0.456 | 0.923 | 3.5E-09 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 1995 | 2018 | ||||||||
|
NLR family pyrin domain containing 2 | 0.515 | 0.731 | 1.4E-38 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 2002 | 2011 | ||||||||
|
MRE11 homolog, double strand break repair nuclease | 0.527 | 0.808 | 1.3E-12 |
|
disease | 0.090 | None | 1.000 | 9 | 0 | 2003 | 2019 | ||||||||
|
senataxin | 0.570 | 0.731 | 0.95 |
|
disease | 0.080 | None | 0.875 | 8 | 1 | 2004 | 2018 | ||||||||
|
tripartite motif containing 29 | 0.606 | 0.654 | 8.1E-08 |
|
disease | 0.080 | None | 1.000 | 8 | 0 | 1994 | 2019 | ||||||||
|
cyclin dependent kinase inhibitor 1A | 0.403 | 0.769 | 1.9E-03 |
|
disease | 0.080 | None | 0.875 | 6 | 0 | 1995 | 2013 | ||||||||
|
frataxin | 0.510 | 0.654 | 0.34 |
|
disease | 0.070 | None | 0.857 | 7 | 0 | 1989 | 2011 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 2006 | 2019 | ||||||||
|
T cell leukemia/lymphoma 1B | 0.561 | 0.500 | 1.0E-02 |
|
disease | 0.070 | None | 0.857 | 7 | 0 | 1995 | 2004 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 1999 | 2015 | ||||||||
|
T cell leukemia/lymphoma 1A | 0.558 | 0.500 | 5.7E-10 |
|
disease | 0.060 | None | 0.833 | 6 | 0 | 1995 | 2004 | ||||||||
|
T cell receptor beta variable 20/OR9-2 (non-functional) | 0.403 | 0.923 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 1990 | 2014 | |||||||||
|
Thy-1 cell surface antigen | 0.496 | 0.808 | 5.0E-02 |
|
disease | 0.050 | None | 0.800 | 5 | 0 | 1990 | 2000 | ||||||||
|
ETS variant transcription factor 6 | 0.477 | 0.731 | 0.97 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 1995 | 2019 | ||||||||
|
CD38 molecule | 0.407 | 0.885 | 2.3E-06 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 1989 | 1994 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.040 | None | 1.000 | 4 | 2 | 2017 | 2019 | ||||||||
|
serpin family A member 1 | 0.410 | 0.923 | 6.8E-08 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2014 | 2019 | ||||||||
|
X-ray sensitivity | 0.716 | 0.500 |
|
disease | 0.040 | None | 0.750 | 4 | 0 | 1989 | 2014 |