| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
coagulation factor II, thrombin | 0.415 | 0.885 | 1.1E-03 |
|
group | 0.400 | None | 0.960 | 49 | 2 | 1975 | 2020 | ||||||||
|
coagulation factor X | 0.493 | 0.769 | 2.3E-06 |
|
group | 0.400 | None | 1.000 | 30 | 0 | 1976 | 2019 | ||||||||
|
coagulation factor V | 0.441 | 0.846 | 5.9E-15 |
|
group | 0.400 | None | 0.933 | 13 | 1 | 1996 | 2014 | ||||||||
|
kallikrein B1 | 0.604 | 0.692 | 6.3E-13 |
|
group | 0.320 | strong | 1.000 | 2 | 0 | 1974 | 2017 | ||||||||
|
gamma-glutamyl carboxylase | 0.678 | 0.538 | 2.0E-14 |
|
group | 0.320 | None | 1.000 | 2 | 1 | 2000 | 2016 | ||||||||
|
vitamin K epoxide reductase complex subunit 1 | 0.603 | 0.731 | 0.16 |
|
group | 0.310 | None | 1.000 | 1 | 1 | 2008 | 2008 | ||||||||
|
activin A receptor like type 1 | 0.493 | 0.769 | 9.7E-04 |
|
group | 0.310 | strong | 1.000 | 1 | 0 | 2006 | 2006 | ||||||||
|
endoglin | 0.446 | 0.846 | 1.00 |
|
group | 0.310 | strong | 1.000 | 1 | 0 | 2003 | 2006 | ||||||||
|
protein tyrosine phosphatase non-receptor type 11 | 0.385 | 0.923 | 1.00 |
|
group | 0.310 | strong | 1.000 | 1 | 0 | 2002 | 2018 | ||||||||
|
von Willebrand factor | 0.408 | 0.885 | 3.2E-25 |
|
group | 0.100 | None | 0.989 | 94 | 2 | 1988 | 2019 | ||||||||
|
cytochrome c oxidase subunit 8A | 0.400 | 0.846 | 0.12 |
|
group | 0.100 | None | 1.000 | 35 | 0 | 1975 | 2019 | ||||||||
|
coagulation factor IX | 0.465 | 0.885 | 1.00 |
|
group | 0.100 | None | 0.971 | 35 | 0 | 1989 | 2019 | ||||||||
|
coagulation factor III, tissue factor | 0.415 | 0.846 | 1.9E-02 |
|
group | 0.100 | None | 0.960 | 25 | 0 | 1975 | 2019 | ||||||||
|
coagulation factor VIII | 0.542 | 0.769 | 1.00 |
|
group | 0.100 | None | 1.000 | 21 | 0 | 1990 | 2019 | ||||||||
|
thrombomodulin | 0.457 | 0.769 | 5.4E-02 |
|
group | 0.100 | None | 1.000 | 12 | 0 | 2014 | 2020 | ||||||||
|
coagulation factor XI | 0.590 | 0.692 | 3.6E-26 |
|
group | 0.100 | None | 0.818 | 11 | 2 | 1986 | 2019 | ||||||||
|
protein C, inactivator of coagulation factors Va and VIIIa | 0.504 | 0.808 | 1.9E-05 |
|
group | 0.100 | None | 1.000 | 10 | 0 | 1995 | 2019 | ||||||||
|
proline rich protein BstNI subfamily 2 | 0.610 | 0.577 | 1.3E-08 |
|
group | 0.090 | None | 1.000 | 9 | 0 | 1999 | 2012 | ||||||||
|
purinergic receptor P2Y12 | 0.533 | 0.731 | 1.7E-03 |
|
group | 0.080 | None | 1.000 | 8 | 1 | 2001 | 2017 | ||||||||
|
lectin, mannose binding 1 | 0.716 | 0.423 | 4.3E-03 |
|
group | 0.080 | None | 1.000 | 8 | 0 | 1999 | 2013 | ||||||||
|
serpin family E member 1 | 0.359 | 0.885 | 4.4E-02 |
|
group | 0.080 | None | 1.000 | 8 | 0 | 1996 | 2020 | ||||||||
|
serpin family F member 2 | 0.575 | 0.808 | 1.4E-02 |
|
group | 0.070 | None | 1.000 | 7 | 0 | 1982 | 2008 | ||||||||
|
chromosome 20 open reading frame 181 | 0.479 | 0.885 |
|
group | 0.070 | None | 1.000 | 7 | 0 | 1994 | 2019 | |||||||||
|
ADAM metallopeptidase with thrombospondin type 1 motif 13 | 0.496 | 0.769 | 5.1E-15 |
|
group | 0.070 | None | 1.000 | 7 | 0 | 2018 | 2019 | ||||||||
|
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit | 0.716 | 0.269 | 0.10 |
|
group | 0.060 | None | 1.000 | 6 | 0 | 2005 | 2013 |