Source: CLINVAR

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.700 None 0.947 1 68 1991 2019
Entrez Id: 238
Gene Symbol: ALK
ALK
ALK receptor tyrosine kinase 0.396 0.846 3.2E-06
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.610 None 1.000 1 3 2009 2012
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.500 None 1.000 3 3 2010 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.500 None 1.000 3 4 1999 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.500 None 0.981 2 7 1988 2019
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
isocitrate dehydrogenase (NADP(+)) 1 0.424 0.808 2.6E-12
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.500 None 1.000 2 2 2008 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.480 None 0.889 1 2 2002 2017
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.200 None 1.000 1 20 2004 2018
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
isocitrate dehydrogenase (NADP(+)) 2 0.434 0.808 0.88
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.200 None 1.000 1 2 2010 2018
Entrez Id: 3020
Gene Symbol: H3-3A
H3-3A
H3.3 histone A 0.559 0.692 0.12
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.130 None 1.000 1 1 2013 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.390 0.808 0.49
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.130 None 1.000 1 2 2001 2016
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1 0.477 0.885 1.00
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.100 None 1.000 1 2 2016 2016
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
protein tyrosine phosphatase non-receptor type 11 0.385 0.923 1.00
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
group 0.100 None 1.000 1 2 2016 2016