Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.390 0.808 0.49
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.510 None 1.000 1 0 1987 2014
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.400 None 1.000 21 2 2005 2019
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
thymidylate synthetase 0.425 0.846 0.72
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.400 None 0.947 18 0 2001 2017
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.370 None 1.000 7 1 1994 2018
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
cyclin dependent kinase inhibitor 1B 0.409 0.769 0.62
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.330 None 1.000 3 0 2001 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 0.881 42 3 1994 2020
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 0.975 40 1 1987 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
CEA cell adhesion molecule 5 0.420 0.846 4.2E-10
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 0.950 20 0 2005 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 0.947 19 2 2009 2019
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.399 0.808 3.4E-05
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 0.923 13 2 1998 2014
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
single-strand-selective monofunctional uracil-DNA glycosylase 1 0.322 0.923 4.5E-04
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 0.923 13 0 2017 2020
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
mutS homolog 2 0.406 0.808 0.90
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 0.909 11 0 1998 2015
Entrez Id: 29126
Gene Symbol: CD274
CD274
CD274 molecule 0.324 0.923 1.9E-02
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 1.000 10 0 2017 2019
Entrez Id: 811
Gene Symbol: CALR
CALR
calreticulin 0.413 0.923 0.89
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 0.900 10 0 2017 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 0.900 10 3 2005 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 1.000 10 0 2002 2019
Entrez Id: 799
Gene Symbol: CALCR
CALCR
calcitonin receptor 0.464 0.846 3.1E-09
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 0.900 10 0 2017 2019
Entrez Id: 6535
Gene Symbol: SLC6A8
SLC6A8
solute carrier family 6 member 8 0.476 0.846 1.00
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 0.900 10 0 2017 2019
Entrez Id: 158809
Gene Symbol: MAGEB6
MAGEB6
MAGE family member B6 0.760 0.115
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.100 None 1.000 10 0 2007 2019
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.090 None 1.000 9 0 2010 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR
vitamin D receptor 0.352 0.885 1.7E-05
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.090 None 1.000 9 1 2000 2010
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
mannose receptor C-type 1 0.413 0.846 0.94
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.070 None 0.857 7 0 2003 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
C-reactive protein 0.299 0.962 3.7E-03
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.070 None 0.857 7 1 2011 2019
Entrez Id: 213
Gene Symbol: ALB
ALB
albumin 0.317 0.962 0.64
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.070 None 1.000 7 0 2017 2019
Entrez Id: 960
Gene Symbol: CD44
CD44
CD44 molecule (Indian blood group) 0.363 0.962 2.4E-07
CUI: C0007113
Disease: Rectal Carcinoma
Rectal Carcinoma
disease 0.070 None 1.000 7 1 2012 2019