| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
myocilin | 0.595 | 0.500 | 7.6E-12 |
|
disease | 0.700 | None | 0.979 | 146 | 21 | 1995 | 2019 | ||||||||
|
latent transforming growth factor beta binding protein 2 | 0.572 | 0.692 | 7.4E-04 |
|
disease | 0.480 | None | 1.000 | 10 | 0 | 2009 | 2018 | ||||||||
|
cyclin dependent kinase inhibitor 2B | 0.417 | 0.769 | 7.3E-03 |
|
disease | 0.450 | None | 1.000 | 6 | 2 | 2011 | 2017 | ||||||||
|
solute carrier family 4 member 4 | 0.644 | 0.692 | 1.00 |
|
disease | 0.430 | None | 1.000 | 4 | 0 | 2004 | 2018 | ||||||||
|
paired like homeodomain 2 | 0.489 | 0.808 | 0.98 |
|
disease | 0.400 | None | 1.000 | 13 | 0 | 2002 | 2018 | ||||||||
|
transforming growth factor beta 2 | 0.433 | 0.885 | 1.00 |
|
disease | 0.400 | None | 1.000 | 12 | 0 | 2007 | 2019 | ||||||||
|
brain derived neurotrophic factor | 0.345 | 0.923 | 0.66 |
|
disease | 0.360 | None | 0.875 | 8 | 2 | 2000 | 2018 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
disease | 0.320 | None | 1.000 | 2 | 0 | 2011 | 2015 | ||||||||
|
myosin light chain kinase | 0.510 | 0.846 | 9.2E-12 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2010 | 2010 | ||||||||
|
tudor domain containing 7 | 0.751 | 0.346 | 6.1E-04 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2011 | 2011 | ||||||||
|
SH3 and PX domains 2B | 0.631 | 0.577 | 4.2E-03 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.300 | None | 0.875 | 16 | 4 | 2002 | 2019 | ||||||||
|
C3 and PZP like alpha-2-macroglobulin domain containing 8 | 0.722 | 0.231 | 6.9E-23 |
|
disease | 0.300 | strong | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
vascular endothelial growth factor A | 0.266 | 0.923 | 2.4E-05 |
|
disease | 0.270 | None | 1.000 | 9 | 0 | 2008 | 2019 | ||||||||
|
neurotrophic receptor tyrosine kinase 2 | 0.479 | 0.808 | 1.00 |
|
disease | 0.220 | None | 1.000 | 4 | 0 | 2000 | 2019 | ||||||||
|
synuclein gamma | 0.550 | 0.615 | 8.5E-04 |
|
disease | 0.220 | None | 1.000 | 3 | 0 | 2002 | 2020 | ||||||||
|
ciliary neurotrophic factor | 0.561 | 0.615 | 2.3E-05 |
|
disease | 0.210 | None | 0.500 | 2 | 0 | 2004 | 2017 | ||||||||
|
beclin 1 | 0.432 | 0.846 | 0.94 |
|
disease | 0.210 | None | 1.000 | 2 | 0 | 2012 | 2018 | ||||||||
|
BCL2 associated X, apoptosis regulator | 0.417 | 0.885 | 0.32 |
|
disease | 0.210 | None | 1.000 | 2 | 0 | 2013 | 2017 | ||||||||
|
thioredoxin | 0.447 | 0.885 | 0.20 |
|
disease | 0.210 | None | 1.000 | 2 | 0 | 2009 | 2012 | ||||||||
|
sequestosome 1 | 0.428 | 0.885 | 8.6E-04 |
|
disease | 0.210 | None | 1.000 | 2 | 0 | 2013 | 2016 | ||||||||
|
nerve growth factor | 0.391 | 0.885 | 0.82 |
|
disease | 0.210 | None | 1.000 | 2 | 0 | 2009 | 2017 | ||||||||
|
cyclin dependent kinase inhibitor 1B | 0.409 | 0.769 | 0.62 |
|
disease | 0.210 | None | 1.000 | 2 | 0 | 2006 | 2016 | ||||||||
|
cytochrome P450 family 1 subfamily B member 1 | 0.457 | 0.769 | 2.2E-05 |
|
disease | 0.200 | None | 0.979 | 47 | 5 | 2000 | 2017 | ||||||||
|
forkhead box C1 | 0.483 | 0.846 | 0.95 |
|
disease | 0.200 | None | 1.000 | 28 | 4 | 1998 | 2020 |