Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.800 None 1.000 60 2 2010 2019
Entrez Id: 909
Gene Symbol: CD1A
CD1A
CD1a molecule 0.543 0.769 4.2E-24
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.100 None 0.957 23 0 2001 2020
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
mitogen-activated protein kinase kinase 1 0.439 0.846 0.90
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.100 None 1.000 13 0 2014 2019
Entrez Id: 50489
Gene Symbol: CD207
CD207
CD207 molecule 0.631 0.692 2.8E-06
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.100 None 0.833 12 0 2006 2020
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1
mitogen-activated protein kinase 1 0.330 0.923 1.00
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.100 None 1.000 10 0 2015 2019
Entrez Id: 2048
Gene Symbol: EPHB2
EPHB2
EPH receptor B2 0.374 0.846 1.00
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.100 None 1.000 10 0 2015 2019
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
Raf-1 proto-oncogene, serine/threonine kinase 0.418 0.885 0.85
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.080 None 1.000 8 1 2010 2019
Entrez Id: 22882
Gene Symbol: ZHX2
ZHX2
zinc fingers and homeoboxes 2 0.510 0.654 3.4E-02
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.080 None 1.000 8 0 2010 2019
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7
mitogen-activated protein kinase kinase 7 0.419 0.808 1.00
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.070 None 1.000 7 0 2015 2019
Entrez Id: 6271
Gene Symbol: S100A1
S100A1
S100 calcium binding protein A1 0.421 0.846 6.0E-03
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.060 None 0.833 6 0 1992 2019
Entrez Id: 6285
Gene Symbol: S100B
S100B
S100 calcium binding protein B 0.383 0.923 4.4E-02
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.060 None 0.833 6 0 1992 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.050 None 1.000 5 0 2002 2019
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.040 None 1.000 4 0 1997 2018
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
interleukin 17A 0.324 0.923 4.3E-02
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.040 None 1.000 4 0 2011 2020
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
single-strand-selective monofunctional uracil-DNA glycosylase 1 0.322 0.923 4.5E-04
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.030 None 1.000 3 0 2017 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.030 None 1.000 3 0 1997 2019
Entrez Id: 3973
Gene Symbol: LHCGR
LHCGR
luteinizing hormone/choriogonadotropin receptor 0.528 0.692 5.3E-08
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.030 None 1.000 3 5 1995 2018
Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B
TNF receptor superfamily member 11b 0.422 0.808 0.16
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.030 None 1.000 3 0 2017 2019
Entrez Id: 369
Gene Symbol: ARAF
ARAF
A-Raf proto-oncogene, serine/threonine kinase 0.619 0.654 0.96
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.030 None 1.000 3 0 2014 2015
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
interleukin 1 alpha 0.333 0.962 1.6E-04
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.030 None 1.000 3 0 1997 2018
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
platelet and endothelial cell adhesion molecule 1 0.426 0.846
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.030 None 1.000 3 0 2003 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.030 None 1.000 3 0 2014 2019
Entrez Id: 3714
Gene Symbol: JAG2
JAG2
jagged canonical Notch ligand 2 0.576 0.846 1.00
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.020 None 1.000 2 0 2012 2019
Entrez Id: 367
Gene Symbol: AR
AR
androgen receptor 0.351 0.846 0.99
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.020 None 1.000 2 0 1994 2010
Entrez Id: 50964
Gene Symbol: SOST
SOST
sclerostin 0.474 0.808 0.87
CUI: C0019621
Disease: Histiocytosis, Langerhans-Cell
Histiocytosis, Langerhans-Cell
disease 0.020 None 1.000 2 0 2017 2018