| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
patched 1 | 0.398 | 0.885 | 1.00 |
|
disease | 0.900 | None | 0.985 | 0 | 1 | 1997 | 2020 | ||||||||
|
SUFU negative regulator of hedgehog signaling | 0.493 | 0.769 | 1.00 |
|
disease | 0.800 | definitive | 0.950 | 3 | 14 | 1996 | 2019 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.800 | None | 0.979 | 2 | 9 | 1998 | 2020 | ||||||||
|
smoothened, frizzled class receptor | 0.489 | 0.731 | 4.3E-07 |
|
disease | 0.690 | None | 1.000 | 2 | 1 | 2000 | 2020 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.630 | strong | 1.000 | 0 | 22 | 2003 | 2018 | ||||||||
|
patched 2 | 0.563 | 0.692 | 3.4E-16 |
|
disease | 0.610 | moderate | 1.000 | 0 | 1 | 1999 | 1999 | ||||||||
|
MYCN proto-oncogene, bHLH transcription factor | 0.454 | 0.808 | 0.89 |
|
disease | 0.500 | None | 0.971 | 1 | 1 | 1989 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.200 | None | 0.974 | 1 | 8 | 1991 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.200 | None | 1.000 | 1 | 7 | 2004 | 2019 | ||||||||
|
CREB binding protein | 0.428 | 0.808 | 1.00 |
|
disease | 0.120 | None | 1.000 | 1 | 2 | 2012 | 2016 | ||||||||
|
isocitrate dehydrogenase (NADP(+)) 1 | 0.424 | 0.808 | 2.6E-12 |
|
disease | 0.110 | None | 1.000 | 1 | 2 | 2016 | 2018 | ||||||||
|
F-box and WD repeat domain containing 7 | 0.465 | 0.808 | 1.00 |
|
disease | 0.110 | None | 1.000 | 1 | 2 | 2016 | 2016 | ||||||||
|
splicing factor 3b subunit 2 | 0.780 | 0.308 | 1.00 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2016 | 2016 | ||||||||
|
E1A binding protein p300 | 0.459 | 0.846 | 1.00 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2016 | 2016 | ||||||||
|
fibroblast growth factor receptor 1 | 0.362 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 1 | 5 | 2016 | 2016 | ||||||||
|
NRAS proto-oncogene, GTPase | 0.390 | 0.808 | 0.49 |
|
disease | 0.100 | None | 1.000 | 1 | 2 | 2016 | 2016 | ||||||||
|
MYCN opposite strand | 0.700 | 0.462 |
|
disease | 0.100 | None | 1.000 | 1 | 1 | 2016 | 2016 | |||||||||
|
WRN RecQ like helicase | 0.524 | 0.808 | 2.6E-34 |
|
disease | 0.100 | None | 0 | 1 |