| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
synuclein alpha | 0.427 | 0.885 | 0.88 |
|
disease | 0.700 | None | 0.983 | 29 | 34 | 1997 | 2020 | ||||||||
|
parkin RBR E3 ubiquitin protein ligase | 0.431 | 0.846 | 6.9E-07 |
|
disease | 0.600 | None | 0.974 | 13 | 0 | 1998 | 2020 | ||||||||
|
Parkinsonism associated deglycase | 0.535 | 0.808 | 0.75 |
|
disease | 0.600 | None | 0.973 | 9 | 0 | 2003 | 2020 | ||||||||
|
PTEN induced kinase 1 | 0.516 | 0.769 | 1.9E-10 |
|
disease | 0.600 | None | 0.987 | 5 | 0 | 2002 | 2020 | ||||||||
|
ATPase cation transporting 13A2 | 0.566 | 0.577 | 9.0E-09 |
|
disease | 0.600 | strong | 0.946 | 4 | 0 | 2007 | 2019 | ||||||||
|
dopa decarboxylase | 0.535 | 0.769 | 3.8E-08 |
|
disease | 0.600 | None | 1.000 | 2 | 0 | 1988 | 2019 | ||||||||
|
dopamine receptor D2 | 0.436 | 0.846 | 0.75 |
|
disease | 0.600 | None | 0.931 | 1 | 0 | 1995 | 2020 | ||||||||
|
tyrosine hydroxylase | 0.462 | 0.885 | 1.7E-06 |
|
disease | 0.600 | None | 0.979 | 1 | 0 | 1989 | 2020 | ||||||||
|
solute carrier family 18 member A2 | 0.554 | 0.769 | 7.6E-02 |
|
disease | 0.600 | None | 0.966 | 1 | 0 | 1996 | 2020 | ||||||||
|
monoamine oxidase B | 0.533 | 0.808 | 1.00 |
|
disease | 0.600 | None | 0.991 | 1 | 0 | 1993 | 2020 | ||||||||
|
dopamine receptor D1 | 0.529 | 0.808 | 0.96 |
|
disease | 0.570 | None | 1.000 | 1 | 0 | 1996 | 2020 | ||||||||
|
insulin like growth factor 1 receptor | 0.399 | 0.885 | 0.97 |
|
disease | 0.510 | None | 1.000 | 1 | 0 | 2009 | 2019 | ||||||||
|
leucine rich repeat kinase 2 | 0.510 | 0.808 | 2.6E-30 |
|
disease | 0.500 | None | 0.983 | 11 | 6 | 2002 | 2020 | ||||||||
|
glucosylceramidase beta | 0.500 | 0.808 | 1.4E-06 |
|
disease | 0.500 | None | 0.989 | 2 | 1 | 2004 | 2020 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.500 | None | 0.972 | 2 | 24 | 1999 | 2019 | ||||||||
|
cyclin G associated kinase | 0.805 | 0.231 | 5.2E-03 |
|
disease | 0.500 | None | 1.000 | 1 | 3 | 2009 | 2020 | ||||||||
|
bone marrow stromal cell antigen 1 | 0.670 | 0.423 | 4.2E-11 |
|
disease | 0.500 | None | 0.920 | 1 | 7 | 2009 | 2019 | ||||||||
|
major histocompatibility complex, class II, DR alpha | 0.581 | 0.769 | 0.52 |
|
disease | 0.480 | None | 1.000 | 1 | 1 | 2010 | 2015 | ||||||||
|
solute carrier family 6 member 3 | 0.453 | 0.885 | 1.00 |
|
disease | 0.400 | None | 0.935 | 4 | 0 | 1994 | 2020 | ||||||||
|
superoxide dismutase 1 | 0.379 | 0.962 | 0.18 |
|
disease | 0.400 | None | 0.971 | 3 | 0 | 1993 | 2020 | ||||||||
|
superoxide dismutase 2 | 0.379 | 0.923 | 0.15 |
|
disease | 0.400 | None | 1.000 | 3 | 0 | 1997 | 2019 | ||||||||
|
glial cell derived neurotrophic factor | 0.434 | 0.885 | 0.20 |
|
disease | 0.400 | None | 0.983 | 2 | 0 | 1993 | 2020 | ||||||||
|
Parkinson disease 16 (susceptibility) | 0.861 | 0.077 |
|
disease | 0.400 | None | 0.963 | 2 | 0 | 2009 | 2019 | |||||||||
|
ceruloplasmin | 0.466 | 0.846 | 4.2E-10 |
|
disease | 0.400 | None | 0.938 | 2 | 0 | 2004 | 2020 | ||||||||
|
cytochrome P450 family 2 subfamily D member 6 | 0.437 | 0.885 | 1.1E-25 |
|
disease | 0.400 | None | 0.879 | 2 | 0 | 1992 | 2019 |