| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
5'-aminolevulinate synthase 1 | 0.705 | 0.462 | 0.11 |
|
group | 0.520 | None | 1.000 | 4 | 0 | 1995 | 2019 | ||||||||
|
uroporphyrinogen decarboxylase | 0.521 | 0.769 | 1.3E-08 |
|
group | 0.100 | None | 1.000 | 17 | 1 | 1986 | 2019 | ||||||||
|
hydroxymethylbilane synthase | 0.559 | 0.731 | 0.95 |
|
group | 0.080 | None | 1.000 | 8 | 2 | 1978 | 2013 | ||||||||
|
aminolevulinate dehydratase | 0.556 | 0.615 | 5.6E-05 |
|
group | 0.080 | None | 1.000 | 8 | 0 | 1981 | 2014 | ||||||||
|
protoporphyrinogen oxidase | 0.678 | 0.500 | 2.8E-02 |
|
group | 0.050 | None | 1.000 | 5 | 1 | 1997 | 2011 | ||||||||
|
coproporphyrinogen oxidase | 0.488 | 0.846 | 0.17 |
|
group | 0.040 | None | 1.000 | 4 | 0 | 1995 | 2011 | ||||||||
|
ferrochelatase | 0.585 | 0.577 | 2.8E-03 |
|
group | 0.040 | None | 1.000 | 4 | 0 | 1982 | 2016 | ||||||||
|
homeostatic iron regulator | 0.436 | 0.846 | 2.6E-08 |
|
group | 0.030 | None | 1.000 | 3 | 2 | 1999 | 2019 | ||||||||
|
uroporphyrinogen III synthase | 0.678 | 0.462 | 3.2E-02 |
|
group | 0.020 | None | 1.000 | 2 | 1 | 2016 | 2019 | ||||||||
|
lamin A/C | 0.384 | 0.885 | 1.00 |
|
group | 0.020 | None | 1.000 | 2 | 0 | 2013 | 2017 | ||||||||
|
5'-aminolevulinate synthase 2 | 0.606 | 0.577 | 1.00 |
|
group | 0.020 | None | 0.500 | 2 | 0 | 2019 | 2019 | ||||||||
|
calcitonin related polypeptide alpha | 0.416 | 0.923 | 1.6E-02 |
|
group | 0.020 | None | 1.000 | 2 | 0 | 1989 | 1989 | ||||||||
|
ATP binding cassette subfamily B member 6 (Langereis blood group) | 0.431 | 0.885 | 8.6E-19 |
|
group | 0.020 | None | 1.000 | 2 | 0 | 2016 | 2017 | ||||||||
|
SH2 domain containing 1A | 0.525 | 0.731 | 0.39 |
|
group | 0.010 | None | 1.000 | 1 | 0 | 2015 | 2015 | ||||||||
|
hepcidin antimicrobial peptide | 0.433 | 0.846 | 8.2E-03 |
|
group | 0.010 | None | 1.000 | 1 | 0 | 2008 | 2008 | ||||||||
|
solute carrier family 15 member 2 | 0.805 | 0.308 | 5.5E-20 |
|
group | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
keratin 18 | 0.530 | 0.692 | 0.73 |
|
group | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
1,4-alpha-glucan branching enzyme 1 | 0.612 | 0.654 | 1.1E-12 |
|
group | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
GATA binding protein 1 | 0.483 | 0.808 | 0.95 |
|
group | 0.010 | None | 1.000 | 1 | 0 | 2007 | 2007 | ||||||||
|
erythropoietin | 0.381 | 0.885 | 1.1E-02 |
|
group | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
cytochrome P450 family 3 subfamily A member 4 | 0.462 | 0.885 | 5.8E-11 |
|
group | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
cytochrome P450 family 2 subfamily D member 6 | 0.437 | 0.885 | 1.1E-25 |
|
group | 0.010 | None | 1.000 | 1 | 0 | 2007 | 2007 | ||||||||
|
cytochrome P450 family 2 subfamily B member 6 | 0.428 | 0.846 | 1.9E-10 |
|
group | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
group | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
PPARG coactivator 1 alpha | 0.453 | 0.885 | 1.00 |
|
group | 0.010 | None | 1.000 | 1 | 0 | 2005 | 2005 |