Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 32 4 1999 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
Secondary malignant neoplasm of lung
disease 0.100 None 0.969 32 0 1989 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
Secondary malignant neoplasm of lung
disease 0.100 None 0.929 28 1 1987 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 23 0 2006 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
Secondary malignant neoplasm of lung
disease 0.100 None 0.955 22 2 1999 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.333 0.923 0.84
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 18 0 2005 2020
Entrez Id: 29126
Gene Symbol: CD274
CD274
CD274 molecule 0.324 0.923 1.9E-02
Secondary malignant neoplasm of lung
disease 0.100 None 0.941 17 0 2015 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
Secondary malignant neoplasm of lung
disease 0.100 None 0.941 17 3 2006 2019
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
CEA cell adhesion molecule 5 0.420 0.846 4.2E-10
Secondary malignant neoplasm of lung
disease 0.100 None 0.938 16 0 2009 2019
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
C-X-C motif chemokine receptor 4 0.362 0.923 1.8E-02
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 16 0 2005 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 14 0 2006 2019
Entrez Id: 3558
Gene Symbol: IL2
IL2
interleukin 2 0.336 0.885 0.48
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 12 0 1993 2018
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.305 0.923 1.9E-17
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 12 0 2005 2019
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 12 0 1995 2019
Entrez Id: 960
Gene Symbol: CD44
CD44
CD44 molecule (Indian blood group) 0.363 0.962 2.4E-07
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 12 0 1997 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 11 0 2013 2019
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
Secondary malignant neoplasm of lung
disease 0.100 None 0.909 11 0 2010 2019
Entrez Id: 7431
Gene Symbol: VIM
VIM
vimentin 0.372 0.846 0.71
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 11 0 2015 2020
Entrez Id: 857
Gene Symbol: CAV1
CAV1
caveolin 1 0.388 0.885 8.3E-03
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 11 0 2004 2019
Entrez Id: 10630
Gene Symbol: PDPN
PDPN
podoplanin 0.470 0.769 3.2E-04
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 10 0 2007 2019
Entrez Id: 1822
Gene Symbol: ATN1
ATN1
atrophin 1 0.409 0.885 1.00
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 10 0 2011 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
Secondary malignant neoplasm of lung
disease 0.100 None 0.900 10 0 1992 2020
Entrez Id: 5175
Gene Symbol: PECAM1
PECAM1
platelet and endothelial cell adhesion molecule 1 0.426 0.846
Secondary malignant neoplasm of lung
disease 0.100 None 1.000 10 0 1995 2019
Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
single-strand-selective monofunctional uracil-DNA glycosylase 1 0.322 0.923 4.5E-04
Secondary malignant neoplasm of lung
disease 0.090 None 1.000 9 0 2017 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
Secondary malignant neoplasm of lung
disease 0.090 None 1.000 9 1 2010 2019