| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
TBC1 domain family member 7 | 0.729 | 0.385 | 2.9E-12 |
|
disease | 0.620 | moderate | 1.000 | 2 | 0 | 2013 | 2014 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.500 | strong | 0.976 | 41 | 3 | 1998 | 2019 | ||||||||
|
chromodomain helicase DNA binding protein 8 | 0.656 | 0.577 | 1.00 |
|
disease | 0.490 | None | 1.000 | 10 | 0 | 2012 | 2020 | ||||||||
|
chromodomain helicase DNA binding protein 3 | 0.670 | 0.577 | 1.00 |
|
disease | 0.440 | strong | 1.000 | 5 | 0 | 2018 | 2019 | ||||||||
|
bromodomain and WD repeat domain containing 3 | 0.716 | 0.538 | 1.00 |
|
disease | 0.430 | strong | 1.000 | 4 | 0 | 2007 | 2019 | ||||||||
|
nuclear factor I B | 0.573 | 0.654 | 1.00 |
|
disease | 0.410 | moderate | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
cyclin D2 | 0.477 | 0.808 | 0.99 |
|
disease | 0.400 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
thyroid hormone receptor alpha | 0.566 | 0.769 | 0.33 |
|
disease | 0.310 | strong | 1.000 | 2 | 0 | 2015 | 2016 | ||||||||
|
ornithine decarboxylase 1 | 0.510 | 0.731 | 0.17 |
|
disease | 0.310 | strong | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
calcium voltage-gated channel subunit alpha1 E | 0.650 | 0.577 | 1.00 |
|
disease | 0.300 | strong | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
tet methylcytosine dioxygenase 3 | 0.633 | 0.615 | 1.00 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.200 | None | 1.000 | 17 | 1 | 2012 | 2019 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.200 | None | 1.000 | 12 | 0 | 2014 | 2019 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.200 | None | 1.000 | 10 | 1 | 2015 | 2019 | ||||||||
|
AKT serine/threonine kinase 3 | 0.512 | 0.808 | 1.00 |
|
disease | 0.170 | None | 1.000 | 7 | 0 | 2013 | 2017 | ||||||||
|
modulator of VRAC current 1 | 0.585 | 0.769 | 3.2E-08 |
|
disease | 0.140 | None | 1.000 | 4 | 0 | 2011 | 2017 | ||||||||
|
sprouty related EVH1 domain containing 1 | 0.644 | 0.577 | 0.97 |
|
disease | 0.140 | None | 1.000 | 4 | 0 | 2009 | 2016 | ||||||||
|
nuclear receptor binding SET domain protein 1 | 0.505 | 0.769 | 1.00 |
|
disease | 0.130 | None | 1.000 | 3 | 0 | 2005 | 2013 | ||||||||
|
phosphoinositide-3-kinase regulatory subunit 2 | 0.551 | 0.808 | 1.6E-02 |
|
disease | 0.120 | None | 1.000 | 2 | 0 | 2015 | 2016 | ||||||||
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.674 | 0.500 | 1.00 |
|
disease | 0.120 | None | 1.000 | 2 | 0 | 2016 | 2016 | ||||||||
|
kaptin, actin binding protein | 0.769 | 0.192 | 1.1E-05 |
|
disease | 0.120 | None | 1.000 | 2 | 0 | 2014 | 2015 | ||||||||
|
hepatic and glial cell adhesion molecule | 0.621 | 0.500 | 0.87 |
|
disease | 0.120 | None | 0.500 | 2 | 0 | 2011 | 2014 | ||||||||
|
OFD1 centriole and centriolar satellite protein | 0.510 | 0.808 | 0.96 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2006 | 2006 | ||||||||
|
HRas proto-oncogene, GTPase | 0.378 | 0.885 | 8.0E-02 |
|
disease | 0.110 | None | 1.000 | 1 | 1 | 2012 | 2012 | ||||||||
|
collagen type II alpha 1 chain | 0.444 | 0.846 | 1.00 |
|
disease | 0.110 | None | 1.000 | 1 | 0 | 2000 | 2000 |