| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
serpin family A member 1 | 0.410 | 0.923 | 6.8E-08 |
|
disease | 0.700 | None | 0.978 | 172 | 3 | 1978 | 2020 | ||||||||
|
Pulmonary disease, chronic obstructive, severe early-onset | 0.456 | 0.885 |
|
disease | 0.100 | None | 1.000 | 22 | 0 | 2000 | 2019 | |||||||||
|
elastase, neutrophil expressed | 0.447 | 0.846 | 1.2E-03 |
|
disease | 0.100 | None | 0.923 | 13 | 0 | 1981 | 2019 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1997 | 2012 | ||||||||
|
elastin | 0.415 | 0.885 | 2.1E-14 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2003 | 2019 | ||||||||
|
serpin family A member 13, pseudogene | 0.619 | 0.692 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1995 | 2005 | |||||||||
|
homeostatic iron regulator | 0.436 | 0.846 | 2.6E-08 |
|
disease | 0.030 | None | 1.000 | 3 | 1 | 2005 | 2017 | ||||||||
|
serpin family A member 3 | 0.486 | 0.846 | 8.8E-14 |
|
disease | 0.030 | None | 0.667 | 3 | 0 | 1985 | 1990 | ||||||||
|
serpin family G member 1 | 0.507 | 0.769 | 0.96 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2003 | 2011 | ||||||||
|
adrenoceptor alpha 1D | 0.636 | 0.731 | 4.0E-05 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2017 | 2018 | ||||||||
|
alpha-2-macroglobulin | 0.529 | 0.769 | 4.5E-11 |
|
disease | 0.020 | None | 0.500 | 2 | 0 | 1981 | 1983 | ||||||||
|
catalase | 0.359 | 0.962 | 1.6E-10 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2015 | 2017 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.020 | None | 1.000 | 1 | 0 | 2007 | 2008 | ||||||||
|
selenoprotein S | 0.628 | 0.615 | 1.4E-09 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2013 | 2013 | ||||||||
|
hepcidin antimicrobial peptide | 0.433 | 0.846 | 8.2E-03 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2015 | 2015 | ||||||||
|
UDP-glucose glycoprotein glucosyltransferase 1 | 0.682 | 0.385 | 5.2E-10 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2013 | 2013 | ||||||||
|
proteinase 3 | 0.503 | 0.808 | 3.8E-05 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 1999 | 1999 | ||||||||
|
PROP paired-like homeobox 1 | 0.576 | 0.615 | 8.8E-02 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
transmembrane BAX inhibitor motif containing 4 | 0.743 | 0.500 | 3.9E-06 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||||||
|
interleukin 17D | 0.464 | 0.808 | 0.20 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
myeloid derived growth factor | 0.451 | 0.846 | 3.5E-06 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
ATPase copper transporting beta | 0.529 | 0.654 | 4.8E-30 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2019 | 2019 | ||||||||
|
FEV transcription factor, ETS family member | 0.593 | 0.692 | 8.1E-03 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2005 | 2005 | ||||||||
|
Pim-1 proto-oncogene, serine/threonine kinase | 0.482 | 0.769 | 0.85 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 1987 | 1987 | ||||||||
|
DnaJ heat shock protein family (Hsp40) member B11 | 0.751 | 0.346 | 0.23 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2017 | 2017 |