×
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
Fibrosis, Liver
0.500
Biomarker
CTD_human
Tumor formation in liver of conditional β-catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen.
21047994 2011
×
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4
Fibrosis, Liver
0.450
Biomarker
CTD_human
Integrin alphavbeta6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies.
18221819 2008
×
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4
Fibrosis, Liver
0.450
Biomarker
CTD_human
Effects of Ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene.
8698195 1996
×
Entrez Id: 91147
Gene Symbol: TMEM67
TMEM67
Fibrosis, Liver
0.440
Biomarker
CTD_human
Hypomorphic MKS3 /TMEM67 mutations cause NPHP with liver fibrosis (NPHP11).
19508969 2009
×
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
Fibrosis, Liver
0.400
Biomarker
CTD_human
Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis.
26396155 2016
×
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
Fibrosis, Liver
0.400
Biomarker
CTD_human
Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis.
26396155 2016
LGALS3BP
Fibrosis, Liver
0.400
Biomarker
CTD_human
Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis.
26396155 2016
×
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
Fibrosis, Liver
0.400
Biomarker
CTD_human
Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis.
26396155 2016
SERPINA1
Fibrosis, Liver
0.400
Biomarker
CTD_human
Ni(ii) ions cleave and inactivate human alpha-1 antitrypsin hydrolytically, implicating nickel exposure as a contributing factor in pathologies related to antitrypsin deficiency.
25579632 2015
×
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
Fibrosis, Liver
0.400
Biomarker
CTD_human
Ascorbic acid suppresses endotoxemia and NF-κB signaling cascade in alcoholic liver fibrosis in guinea pigs: a mechanistic approach.
24239723 2014
×
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
Fibrosis, Liver
0.400
Biomarker
CTD_human
Precision-cut liver slices as a model for the early onset of liver fibrosis to test antifibrotic drugs.
24321339 2014
×
Entrez Id: 203286
Gene Symbol: ANKS6
ANKS6
Fibrosis, Liver
0.400
Biomarker
CTD_human
We also identify six families with ANKS6 mutations affected by nephronophthisis, including severe cardiovascular abnormalities, liver fibrosis and situs inversus.
23793029 2013
×
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Fibrosis, Liver
0.400
Therapeutic
CTD_human
We also show that Nrf2 may reveal significant gene expression changes, suggesting that Nrf2 activation may ameliorate liver fibrosis .
23793039 2013
×
Entrez Id: 213
Gene Symbol: ALB
ALB
Fibrosis, Liver
0.400
Biomarker
CTD_human
The value of serum ischemia-modified albumin for assessing liver function in patients with chronic liver disease.
21851314 2011
×
Entrez Id: 1277
Gene Symbol: COL1A1
COL1A1
Fibrosis, Liver
0.400
Biomarker
CTD_human
Cannabinoid receptor type I modulates alcohol-induced liver fibrosis.
21863215 2011
×
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
Fibrosis, Liver
0.400
Biomarker
CTD_human
Inhibition of arsenic-induced rat liver injury by grape seed exact through suppression of NADPH oxidase and TGF-β/Smad activation.
21605584 2011
SERPINA1
Fibrosis, Liver
0.400
Biomarker
CTD_human
Rapamycin reduces intrahepatic alpha-1-antitrypsin mutant Z protein polymers and liver injury in a mouse model.
20511674 2010
×
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
Fibrosis, Liver
0.400
Biomarker
CTD_human
The coagulation system contributes to alphaVbeta6 integrin expression and liver fibrosis induced by cholestasis.
21037076 2010
×
Entrez Id: 213
Gene Symbol: ALB
ALB
Fibrosis, Liver
0.400
Biomarker
CTD_human
[Apolipoprotein A in patients with alcoholic liver disease].
17977396 2008
×
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
Fibrosis, Liver
0.400
Biomarker
CTD_human
Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes.
17657819 2007
×
Entrez Id: 3082
Gene Symbol: HGF
HGF
Fibrosis, Liver
0.400
Therapeutic
CTD_human
Effects of hepatotrophic factors on the liver after portacaval shunt in rats with portal hypertension.
17097021 2006
×
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
Fibrosis, Liver
0.400
Biomarker
CTD_human
Osteopontin expression in normal and fibrotic liver. altered liver healing in osteopontin-deficient mice.
16221502 2006
×
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
Fibrosis, Liver
0.400
Biomarker
CTD_human
Therefore, we conducted an investigation to determine if intraportal vein siRNA injection targeting CTGF inhibits CTGF expression on rat liver in vivo and furthermore whether it protects the liver from liver fibrosis .
16652398 2006
×
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
Fibrosis, Liver
0.400
Biomarker
CTD_human
Interleukin-6 protects hepatocytes from CCl4-mediated necrosis and apoptosis in mice by reducing MMP-2 expression.
15763341 2005
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Fibrosis, Liver
0.400
Biomarker
CTD_human
Additionally, IL-6 plasma levels were significantly increased in patients with chronic liver diseases and showed an inverse correlation with biochemical markers of liver function and a positive correlation with inflammatory markers, signs of portal hypertension, and the degree of liver fibrosis .
12830005 2003