Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 326
Gene Symbol: AIRE
AIRE 		autoimmune regulator 0.516 0.808 4.0E-12
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.100 None 0.818 11 0 1998 2019
Entrez Id: 170685
Gene Symbol: NUDT10
NUDT10 		nudix hydrolase 10 0.705 0.423 0.11
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.070 None 0.857 7 0 2000 2019
Entrez Id: 55190
Gene Symbol: NUDT11
NUDT11 		nudix hydrolase 11 0.647 0.615 0.10
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.070 None 0.857 7 0 1998 2019
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1 		major histocompatibility complex, class II, DR beta 1 0.333 0.923 1.1E-03
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.070 None 0.857 7 0 2005 2016
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		cytotoxic T-lymphocyte associated protein 4 0.369 0.923 0.94
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.060 None 1.000 6 1 1998 2015
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22 		protein tyrosine phosphatase non-receptor type 22 0.438 0.846 3.5E-21
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.050 None 0.800 5 1 2008 2016
Entrez Id: 129831
Gene Symbol: RBM45
RBM45 		RNA binding motif protein 45 0.383 0.846 2.1E-10
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.050 None 0.800 5 0 2005 2016
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1 		major histocompatibility complex, class II, DQ alpha 1 0.416 0.846 2.4E-02
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.050 None 1.000 5 0 2003 2016
Entrez Id: 1594
Gene Symbol: CYP27B1
CYP27B1 		cytochrome P450 family 27 subfamily B member 1 0.502 0.769 1.9E-07
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.040 None 1.000 4 0 2005 2016
Entrez Id: 22861
Gene Symbol: NLRP1
NLRP1 		NLR family pyrin domain containing 1 0.502 0.769 5.0E-19
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.040 None 1.000 4 1 2010 2017
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A 		major histocompatibility complex, class I, A 0.370 0.846 1.3E-03
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.040 None 1.000 4 0 2010 2014
Entrez Id: 29126
Gene Symbol: CD274
CD274 		CD274 molecule 0.324 0.923 1.9E-02
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.030 None 1.000 3 0 2009 2016
Entrez Id: 100507436
Gene Symbol: MICA
MICA 		MHC class I polypeptide-related sequence A 0.473 0.846 5.0E-03
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.030 None 1.000 3 0 1999 2014
Entrez Id: 1589
Gene Symbol: CYP21A2
CYP21A2 		cytochrome P450 family 21 subfamily A member 2 0.525 0.769 2.6E-04
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.030 None 1.000 3 1 1992 2014
Entrez Id: 4261
Gene Symbol: CIITA
CIITA 		class II major histocompatibility complex transactivator 0.536 0.808 1.4E-07
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.020 None 1.000 2 0 2006 2014
Entrez Id: 84636
Gene Symbol: GPR174
GPR174 		G protein-coupled receptor 174 0.792 0.231 0.40
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.020 None 1.000 2 1 2015 2016
Entrez Id: 10603
Gene Symbol: SH2B2
SH2B2 		SH2B adaptor protein 2 0.623 0.731 1.5E-05
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.020 None 1.000 2 0 2003 2011
Entrez Id: 5972
Gene Symbol: REN
REN 		renin 0.370 0.923 2.4E-07
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.020 None 1.000 2 0 2018 2019
Entrez Id: 354
Gene Symbol: KLK3
KLK3 		kallikrein related peptidase 3 0.443 0.885 4.4E-06
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.020 None 1.000 2 0 2003 2011
Entrez Id: 64135
Gene Symbol: IFIH1
IFIH1 		interferon induced with helicase C domain 1 0.471 0.808 7.0E-44
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.020 None 0.500 2 1 2013 2013
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		signal transducer and activator of transcription 4 0.471 0.769 0.77
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.020 None 1.000 2 2 2014 2016
Entrez Id: 115352
Gene Symbol: FCRL3
FCRL3 		Fc receptor like 3 0.612 0.769 6.0E-21
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.020 None 1.000 2 0 2007 2016
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		major histocompatibility complex, class I, B 0.379 0.885 3.9E-05
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.020 None 1.000 2 0 2010 2011
Entrez Id: 2625
Gene Symbol: GATA3
GATA3 		GATA binding protein 3 0.415 0.846 0.90
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.020 None 1.000 2 0 2014 2016
Entrez Id: 4772
Gene Symbol: NFATC1
NFATC1 		nuclear factor of activated T cells 1 0.517 0.731 0.16
CUI: C0271737
Disease: Addison's disease due to autoimmunity
Addison's disease due to autoimmunity 		disease 0.020 None 1.000 2 0 2015 2016