| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
translocase of outer mitochondrial membrane 40 | 0.590 | 0.538 | 0.99 |
|
disease | 0.510 | None | 1.000 | 5 | 0 | 2013 | 2018 | ||||||||
|
triggering receptor expressed on myeloid cells 2 | 0.519 | 0.769 | 3.3E-09 |
|
disease | 0.510 | None | 1.000 | 3 | 0 | 2013 | 2017 | ||||||||
|
ATP binding cassette subfamily A member 7 | 0.644 | 0.577 | 2.1E-55 |
|
disease | 0.500 | None | 1.000 | 3 | 0 | 2011 | 2016 | ||||||||
|
amyloid beta precursor protein | 0.422 | 0.846 | 4.7E-02 |
|
disease | 0.400 | None | 0.993 | 35 | 0 | 1988 | 2019 | ||||||||
|
presenilin 1 | 0.469 | 0.846 | 0.97 |
|
disease | 0.400 | None | 0.971 | 13 | 0 | 1988 | 2020 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.400 | None | 0.978 | 9 | 0 | 1993 | 2018 | ||||||||
|
presenilin 2 | 0.550 | 0.654 | 5.4E-04 |
|
disease | 0.400 | None | 0.940 | 3 | 0 | 1995 | 2019 | ||||||||
|
microtubule associated protein tau | 0.446 | 0.923 | 6.0E-03 |
|
disease | 0.350 | None | 1.000 | 7 | 0 | 1992 | 2017 | ||||||||
|
sortilin related receptor 1 | 0.582 | 0.692 | 7.7E-11 |
|
disease | 0.340 | None | 1.000 | 1 | 0 | 2006 | 2018 | ||||||||
|
prion protein | 0.445 | 0.923 | 6.3E-04 |
|
disease | 0.330 | None | 1.000 | 1 | 0 | 2000 | 2013 | ||||||||
|
beta-secretase 1 | 0.559 | 0.769 | 0.88 |
|
disease | 0.330 | None | 1.000 | 1 | 0 | 2006 | 2019 | ||||||||
|
caspase 3 | 0.351 | 0.923 | 0.10 |
|
disease | 0.330 | None | 1.000 | 1 | 0 | 2001 | 2008 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.310 | None | 1.000 | 5 | 0 | 1999 | 2019 | ||||||||
|
alpha-2-macroglobulin | 0.529 | 0.769 | 4.5E-11 |
|
disease | 0.310 | None | 1.000 | 3 | 0 | 1998 | 2016 | ||||||||
|
homeostatic iron regulator | 0.436 | 0.846 | 2.6E-08 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2000 | 2006 | ||||||||
|
glycogen synthase kinase 3 beta | 0.430 | 0.846 | 0.96 |
|
disease | 0.310 | None | 1.000 | 2 | 0 | 2007 | 2013 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2000 | 2007 | ||||||||
|
nicastrin | 0.666 | 0.462 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2005 | 2007 | ||||||||
|
bridging integrator 1 | 0.550 | 0.692 | 0.78 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2011 | 2013 | ||||||||
|
24-dehydrocholesterol reductase | 0.498 | 0.769 | 3.1E-02 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2008 | 2013 | ||||||||
|
interleukin 1 beta | 0.276 | 0.962 | 0.13 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2000 | 2008 | ||||||||
|
ADAM metallopeptidase domain 10 | 0.489 | 0.846 | 1.00 |
|
disease | 0.310 | None | 0.500 | 1 | 0 | 2012 | 2019 | ||||||||
|
insulin degrading enzyme | 0.604 | 0.577 | 6.6E-03 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2007 | 2010 | ||||||||
|
CD2 associated protein | 0.558 | 0.731 | 0.23 |
|
disease | 0.300 | None | 1.000 | 3 | 0 | 2011 | 2018 | ||||||||
|
nectin cell adhesion molecule 2 | 0.575 | 0.769 | 0.97 |
|
disease | 0.300 | None | 1.000 | 3 | 0 | 2018 | 2018 |