| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.200 | None | 0.944 | 18 | 3 | 2000 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.190 | None | 0.889 | 9 | 1 | 1992 | 2020 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.150 | None | 1.000 | 5 | 4 | 2003 | 2009 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.120 | None | 1.000 | 2 | 3 | 2011 | 2018 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.100 | None | 0.952 | 21 | 3 | 1993 | 2018 | ||||||||
|
chromosome 11 open reading frame 65 | 0.670 | 0.462 | 2.0E-14 |
|
disease | 0.100 | None | 0 | 2 | |||||||||||
|
succinate dehydrogenase complex iron sulfur subunit B | 0.474 | 0.846 | 2.4E-04 |
|
disease | 0.100 | None | 0 | 1 | |||||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.100 | None | 0 | 1 | |||||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2008 | 2015 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.030 | None | 0.667 | 3 | 0 | 2002 | 2018 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2005 | 2019 | ||||||||
|
TSC complex subunit 2 | 0.439 | 0.808 | 1.00 |
|
disease | 0.010 | None | < 0.001 | 1 | 0 | 2017 | 2017 | ||||||||
|
ribosomal protein S6 kinase A3 | 0.491 | 0.846 | 1.00 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2015 | 2015 | ||||||||
|
breast cancer 3 | 0.705 | 0.269 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2003 | 2003 | |||||||||
|
polypeptide N-acetylgalactosaminyltransferase 12 | 0.780 | 0.269 | 9.4E-07 |
|
disease | 0.010 | None | 1.000 | 1 | 1 | 2014 | 2014 | ||||||||
|
RAD51 paralog C | 0.533 | 0.692 | 6.2E-14 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2012 | 2012 | ||||||||
|
RAD51 recombinase | 0.447 | 0.846 | 2.7E-02 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2000 | 2000 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2009 | 2009 | ||||||||
|
BRCA1 associated RING domain 1 | 0.597 | 0.538 | 1.4E-24 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||||||
|
NLR family pyrin domain containing 2 | 0.515 | 0.731 | 1.4E-38 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2006 | 2006 | ||||||||
|
cytochrome P450 family 19 subfamily A member 1 | 0.410 | 0.885 | 1.7E-05 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2002 | 2002 | ||||||||
|
dopamine receptor D2 | 0.436 | 0.846 | 0.75 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 1993 | 1993 | ||||||||
|
MCF.2 cell line derived transforming sequence like | 0.559 | 0.769 | 2.7E-07 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2014 | 2014 | ||||||||
|
ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase | 0.427 | 0.885 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 1988 | 1988 | |||||||||
|
hypertrichosis 2 (generalized, congenital) | 0.392 | 0.808 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2004 | 2004 |