| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 1998 | 2007 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.220 | None | 1.000 | 2 | 0 | 2006 | 2016 | ||||||||
|
mutS homolog 6 | 0.462 | 0.731 | 3.7E-05 |
|
disease | 0.120 | None | 1.000 | 2 | 0 | 2009 | 2010 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.100 | None | 1.000 | 17 | 1 | 2000 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 1986 | 2019 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.100 | None | 1.000 | 11 | 0 | 1991 | 2020 | ||||||||
|
CEA cell adhesion molecule 5 | 0.420 | 0.846 | 4.2E-10 |
|
disease | 0.100 | None | 1.000 | 10 | 0 | 1976 | 2018 | ||||||||
|
CD44 molecule (Indian blood group) | 0.363 | 0.962 | 2.4E-07 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2001 | 2019 | ||||||||
|
TBC1 domain family member 9 | 0.399 | 0.846 | 2.8E-05 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 1991 | 2012 | ||||||||
|
DEAD-box helicase 53 | 0.568 | 0.846 | 0.66 |
|
disease | 0.060 | None | 1.000 | 6 | 0 | 2017 | 2019 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.060 | None | 1.000 | 6 | 2 | 2009 | 2019 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 1993 | 2018 | ||||||||
|
microRNA 21 | 0.363 | 0.846 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2016 | 2019 | |||||||||
|
BCL2 apoptosis regulator | 0.291 | 0.885 | 0.56 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2002 | 2019 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2000 | 2018 | ||||||||
|
jagged canonical Notch ligand 1 | 0.429 | 0.808 | 1.00 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2011 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2011 | 2019 | ||||||||
|
mutS homolog 2 | 0.406 | 0.808 | 0.90 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2002 | 2012 | ||||||||
|
TNF superfamily member 10 | 0.413 | 0.885 | 0.13 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2009 | 2019 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2003 | 2017 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2000 | 2007 | ||||||||
|
kallikrein related peptidase 6 | 0.575 | 0.654 | 6.0E-03 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1997 | 2019 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2009 | 2012 | ||||||||
|
SMAD family member 4 | 0.401 | 0.808 | 1.00 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2004 | 2018 | ||||||||
|
thymidylate synthetase | 0.425 | 0.846 | 0.72 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 1989 | 2001 |