| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
phenotype | 0.100 | None | 0.917 | 24 | 0 | 1993 | 2019 | ||||||||
|
pyridoxal phosphatase | 0.533 | 0.731 | 0.26 |
|
phenotype | 0.100 | None | 1.000 | 11 | 0 | 1987 | 2019 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
phenotype | 0.060 | None | 0.833 | 6 | 0 | 1999 | 2017 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
phenotype | 0.060 | None | 1.000 | 6 | 0 | 1999 | 2019 | ||||||||
|
epidermal growth factor receptor | 0.295 | 0.885 | 0.37 |
|
phenotype | 0.040 | None | 1.000 | 4 | 0 | 1999 | 2010 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
phenotype | 0.040 | None | 1.000 | 4 | 0 | 2004 | 2013 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
phenotype | 0.040 | None | 1.000 | 4 | 0 | 1995 | 2019 | ||||||||
|
cytokine inducible SH2 containing protein | 0.500 | 0.808 | 5.4E-04 |
|
phenotype | 0.030 | None | 1.000 | 3 | 0 | 1994 | 2009 | ||||||||
|
carbonic anhydrase 9 | 0.483 | 0.731 | 1.3E-09 |
|
phenotype | 0.030 | None | 1.000 | 3 | 2 | 2013 | 2020 | ||||||||
|
cyclin D1 | 0.344 | 0.923 | 0.89 |
|
phenotype | 0.030 | None | 1.000 | 3 | 0 | 2001 | 2016 | ||||||||
|
fragile histidine triad diadenosine triphosphatase | 0.444 | 0.846 | 5.7E-03 |
|
phenotype | 0.030 | None | 1.000 | 3 | 0 | 2000 | 2017 | ||||||||
|
WW domain containing oxidoreductase | 0.453 | 0.808 | 1.2E-15 |
|
phenotype | 0.020 | None | 1.000 | 2 | 1 | 2008 | 2018 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2011 | 2017 | ||||||||
|
matrix metallopeptidase 26 | 0.650 | 0.615 | 5.4E-11 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2004 | 2006 | ||||||||
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2002 | 2005 | ||||||||
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2014 | 2017 | ||||||||
|
telomerase RNA component | 0.471 | 0.846 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2010 | 2014 | |||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
phenotype | 0.020 | None | 0.500 | 2 | 0 | 2013 | 2019 | ||||||||
|
cytochrome c oxidase subunit II | 0.352 | 0.962 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2008 | 2009 | |||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2007 | 2011 | ||||||||
|
hypoxia inducible factor 1 subunit alpha | 0.327 | 0.923 | 0.98 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2003 | 2020 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2008 | 2009 | ||||||||
|
mutS homolog 2 | 0.406 | 0.808 | 0.90 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2000 | 2013 | ||||||||
|
MET proto-oncogene, receptor tyrosine kinase | 0.380 | 0.846 | 0.97 |
|
phenotype | 0.020 | None | 1.000 | 2 | 0 | 2008 | 2016 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
phenotype | 0.020 | None | 0.500 | 2 | 0 | 2005 | 2019 |