| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
von Hippel-Lindau tumor suppressor | 0.443 | 0.846 | 8.0E-02 |
|
disease | 0.700 | strong | 0.973 | 1 | 0 | 1995 | 2019 | ||||||||
|
folliculin | 0.537 | 0.885 | 0.79 |
|
disease | 0.600 | strong | 1.000 | 0 | 0 | 2002 | 2018 | ||||||||
|
fumarate hydratase | 0.489 | 0.846 | 8.8E-02 |
|
disease | 0.600 | strong | 0.971 | 0 | 0 | 2002 | 2020 | ||||||||
|
BRCA1 associated protein 1 | 0.454 | 0.731 | 0.99 |
|
disease | 0.560 | None | 0.857 | 1 | 0 | 2013 | 2019 | ||||||||
|
interleukin 2 | 0.336 | 0.885 | 0.48 |
|
disease | 0.400 | None | 1.000 | 4 | 0 | 1990 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.400 | None | 1.000 | 0 | 1 | 1993 | 2019 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.400 | strong | 1.000 | 0 | 0 | 1998 | 2019 | ||||||||
|
MET proto-oncogene, receptor tyrosine kinase | 0.380 | 0.846 | 0.97 |
|
disease | 0.390 | strong | 1.000 | 0 | 0 | 1997 | 2019 | ||||||||
|
succinate dehydrogenase complex iron sulfur subunit B | 0.474 | 0.846 | 2.4E-04 |
|
disease | 0.350 | strong | 1.000 | 0 | 0 | 2004 | 2017 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.340 | None | 1.000 | 1 | 0 | 1987 | 2012 | ||||||||
|
glutathione S-transferase theta 1 | 0.393 | 0.923 | 1.5E-04 |
|
disease | 0.340 | None | 1.000 | 1 | 0 | 1997 | 2018 | ||||||||
|
cyclin dependent kinase inhibitor 1B | 0.409 | 0.769 | 0.62 |
|
disease | 0.330 | None | 1.000 | 1 | 0 | 2004 | 2018 | ||||||||
|
N-myc downstream regulated 1 | 0.488 | 0.731 | 1.1E-02 |
|
disease | 0.330 | None | 1.000 | 1 | 0 | 2002 | 2004 | ||||||||
|
TSC complex subunit 2 | 0.439 | 0.808 | 1.00 |
|
disease | 0.320 | None | 1.000 | 3 | 0 | 2001 | 2019 | ||||||||
|
superoxide dismutase 2 | 0.379 | 0.923 | 0.15 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2014 | 2018 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2003 | 2011 | ||||||||
|
cyclin D1 | 0.344 | 0.923 | 0.89 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2011 | 2017 | ||||||||
|
prostaglandin-endoperoxide synthase 2 | 0.314 | 0.962 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2002 | 2017 | ||||||||
|
TNF superfamily member 10 | 0.413 | 0.885 | 0.13 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2006 | 2008 | ||||||||
|
mitogen-activated protein kinase 3 | 0.379 | 0.885 | 3.7E-02 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2011 | 2017 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2011 | 2019 | ||||||||
|
AXL receptor tyrosine kinase | 0.489 | 0.615 | 1.3E-02 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2014 | 2017 | ||||||||
|
cytochrome P450 family 1 subfamily A member 1 | 0.436 | 0.846 | 1.1E-17 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2004 | 2011 | ||||||||
|
neurofibromin 2 | 0.468 | 0.885 | 1.00 |
|
disease | 0.310 | None | 1.000 | 0 | 0 | 2019 | 2019 | ||||||||
|
Ras association domain family member 5 | 0.641 | 0.577 | 4.3E-02 |
|
disease | 0.300 | None | 1.000 | 1 | 0 | 2014 | 2014 |