| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 0.900 | None | 0.947 | 1 | 36 | 1994 | 2020 | ||||||||
|
catenin beta 1 | 0.303 | 0.885 | 1.00 |
|
disease | 0.900 | None | 1.000 | 1 | 4 | 1999 | 2019 | ||||||||
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.700 | None | 0.903 | 8 | 3 | 1991 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.700 | None | 0.984 | 6 | 12 | 1999 | 2019 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
disease | 0.700 | None | 1.000 | 3 | 21 | 1997 | 2019 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 0.700 | None | 0.965 | 1 | 67 | 1992 | 2020 | ||||||||
|
mutS homolog 2 | 0.406 | 0.808 | 0.90 |
|
disease | 0.700 | None | 1.000 | 0 | 3 | 1994 | 2019 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.700 | None | 0.951 | 0 | 1 | 1989 | 2019 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.700 | None | 0.963 | 0 | 170 | 1991 | 2020 | ||||||||
|
opioid binding protein/cell adhesion molecule like | 0.606 | 0.654 | 0.23 |
|
disease | 0.630 | None | 1.000 | 0 | 1 | 2003 | 2014 | ||||||||
|
B-Raf proto-oncogene, serine/threonine kinase | 0.319 | 0.846 | 1.00 |
|
disease | 0.500 | None | 0.958 | 9 | 3 | 2002 | 2019 | ||||||||
|
RAD51 paralog C | 0.533 | 0.692 | 6.2E-14 |
|
disease | 0.500 | None | 0.969 | 0 | 6 | 2010 | 2020 | ||||||||
|
RAD51 paralog D | 0.674 | 0.385 | 1.1E-09 |
|
disease | 0.500 | None | 0.857 | 0 | 4 | 2011 | 2019 | ||||||||
|
BRCA1 interacting protein C-terminal helicase 1 | 0.507 | 0.731 | 6.2E-17 |
|
disease | 0.490 | None | 0.974 | 33 | 44 | 2005 | 2020 | ||||||||
|
cadherin 1 | 0.401 | 0.808 | 0.15 |
|
disease | 0.480 | None | 1.000 | 0 | 2 | 1994 | 2017 | ||||||||
|
parkin RBR E3 ubiquitin protein ligase | 0.431 | 0.846 | 6.9E-07 |
|
disease | 0.460 | None | 1.000 | 0 | 2 | 2003 | 2019 | ||||||||
|
mutS homolog 6 | 0.462 | 0.731 | 3.7E-05 |
|
disease | 0.450 | None | 1.000 | 0 | 5 | 2002 | 2017 | ||||||||
|
PMS1 homolog 2, mismatch repair system component | 0.484 | 0.808 | 4.5E-27 |
|
disease | 0.440 | None | 1.000 | 0 | 1 | 2006 | 2019 | ||||||||
|
RAS related 2 | 0.656 | 0.500 | 0.97 |
|
disease | 0.400 | None | 0 | 1 | |||||||||||
|
X-ray repair cross complementing 2 | 0.512 | 0.731 | 4.0E-07 |
|
disease | 0.200 | None | 0.800 | 0 | 1 | 2005 | 2016 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.200 | None | 0.667 | 0 | 8 | 2008 | 2019 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.200 | None | 0.769 | 0 | 2 | 2002 | 2019 | ||||||||
|
BRCA1 associated RING domain 1 | 0.597 | 0.538 | 1.4E-24 |
|
disease | 0.200 | None | 0.875 | 0 | 1 | 1998 | 2019 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
disease | 0.170 | None | 0.857 | 0 | 5 | 1999 | 2019 | ||||||||
|
checkpoint kinase 1 | 0.492 | 0.808 | 3.1E-08 |
|
disease | 0.160 | None | 1.000 | 0 | 3 | 2012 | 2017 |