| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor necrosis factor | 0.231 | 0.962 | 0.80 |
|
disease | 0.400 | None | 0.950 | 17 | 1 | 1996 | 2018 | ||||||||
|
protein C, inactivator of coagulation factors Va and VIIIa | 0.504 | 0.808 | 1.9E-05 |
|
disease | 0.400 | None | 1.000 | 13 | 1 | 2002 | 2017 | ||||||||
|
interleukin 10 | 0.281 | 0.923 | 5.9E-03 |
|
disease | 0.400 | None | 0.909 | 10 | 0 | 2001 | 2018 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.370 | None | 0.875 | 7 | 1 | 2004 | 2018 | ||||||||
|
lymphotoxin alpha | 0.434 | 0.885 | 0.20 |
|
disease | 0.360 | None | 0.857 | 6 | 0 | 1999 | 2012 | ||||||||
|
high mobility group box 1 | 0.368 | 0.923 | 0.82 |
|
disease | 0.340 | None | 1.000 | 4 | 1 | 2009 | 2017 | ||||||||
|
angiopoietin 1 | 0.446 | 0.808 | 0.95 |
|
disease | 0.320 | None | 1.000 | 2 | 0 | 2005 | 2019 | ||||||||
|
nitric oxide synthase 3 | 0.378 | 0.885 | 6.7E-07 |
|
disease | 0.310 | None | 1.000 | 1 | 1 | 2010 | 2011 | ||||||||
|
caspase 3 | 0.351 | 0.923 | 0.10 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2005 | 2018 | ||||||||
|
lipopolysaccharide binding protein | 0.525 | 0.808 | 4.2E-15 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2009 | 2012 | ||||||||
|
transforming growth factor beta 1 | 0.287 | 0.962 | 3.7E-02 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2005 | 2010 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.100 | None | 0.900 | 10 | 2 | 2002 | 2019 | ||||||||
|
albumin | 0.317 | 0.962 | 0.64 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 2017 | 2018 | ||||||||
|
BTB domain containing 8 | 0.547 | 0.692 | 6.1E-07 |
|
disease | 0.070 | None | 1.000 | 7 | 0 | 2012 | 2018 | ||||||||
|
CD14 molecule | 0.392 | 0.885 | 4.9E-05 |
|
disease | 0.070 | None | 1.000 | 7 | 1 | 2000 | 2017 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
disease | 0.070 | None | 1.000 | 7 | 1 | 2010 | 2019 | ||||||||
|
5'-3' exoribonuclease 1 | 0.716 | 0.346 | 1.00 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2017 | 2019 | ||||||||
|
serpin family E member 1 | 0.359 | 0.885 | 4.4E-02 |
|
disease | 0.050 | None | 1.000 | 5 | 1 | 2004 | 2018 | ||||||||
|
septin 1 | 0.705 | 0.462 | 2.0E-08 |
|
disease | 0.050 | None | 1.000 | 5 | 0 | 2017 | 2019 | ||||||||
|
C-reactive protein | 0.299 | 0.962 | 3.7E-03 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 2018 | 2019 | ||||||||
|
interleukin 1 receptor antagonist | 0.373 | 0.923 | 3.1E-02 |
|
disease | 0.040 | None | 1.000 | 4 | 0 | 1999 | 2018 | ||||||||
|
BCL2 apoptosis regulator | 0.291 | 0.885 | 0.56 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2004 | 2011 | ||||||||
|
triggering receptor expressed on myeloid cells 1 | 0.515 | 0.808 | 6.3E-03 |
|
disease | 0.030 | None | 0.667 | 3 | 1 | 2008 | 2013 | ||||||||
|
angiopoietin 2 | 0.410 | 0.846 | 0.83 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2015 | 2019 | ||||||||
|
lipocalin 2 | 0.405 | 0.885 | 1.1E-09 |
|
disease | 0.030 | None | 1.000 | 3 | 0 | 2014 | 2018 |