Source: MGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 93
Gene Symbol: ACVR2B
ACVR2B
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.700 Biomarker MGD The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse. 9242489

1997
Entrez Id: 118856
Gene Symbol: MMP21
MMP21
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.600 Biomarker MGD

Entrez Id: 7547
Gene Symbol: ZIC3
ZIC3
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.520 Biomarker MGD Zic3 is required in the migrating primitive streak for node morphogenesis and left-right patterning. 23303524

2013
Entrez Id: 7547
Gene Symbol: ZIC3
ZIC3
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.520 Biomarker MGD Zic3 is required in the extra-cardiac perinodal region of the lateral plate mesoderm for left-right patterning and heart development. 23184148

2013
Entrez Id: 7547
Gene Symbol: ZIC3
ZIC3
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.520 Biomarker MGD A complex syndrome of left-right axis, central nervous system and axial skeleton defects in Zic3 mutant mice. 11959836

2002
Entrez Id: 7547
Gene Symbol: ZIC3
ZIC3
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.520 Biomarker MGD The X-linked mouse mutation Bent tail is associated with a deletion of the Zic3 locus. 10942421

2000
Entrez Id: 7547
Gene Symbol: ZIC3
ZIC3
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.520 Biomarker MGD A deletion encompassing Zic3 in bent tail, a mouse model for X-linked neural tube defects. 10861288

2000
Entrez Id: 7547
Gene Symbol: ZIC3
ZIC3
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.520 Biomarker MGD The interfrontal bone and mutant genes in the mouse. 1018005

1976
Entrez Id: 7547
Gene Symbol: ZIC3
ZIC3
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.520 Biomarker MGD """Bent-Tail,"" A Dominant, Sex-Linked Mutation in the Mouse." 16589192

1952
Entrez Id: 55997
Gene Symbol: CFC1
CFC1
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.230 Biomarker MGD

Entrez Id: 8701
Gene Symbol: DNAH11
DNAH11
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.210 Biomarker MGD

Entrez Id: 55130
Gene Symbol: ARMC4
ARMC4
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry. 23849778

2013
Entrez Id: 80173
Gene Symbol: IFT74
IFT74
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD

Entrez Id: 9353
Gene Symbol: SLIT2
SLIT2
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD

Entrez Id: 5125
Gene Symbol: PCSK5
PCSK5
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD

Entrez Id: 8928
Gene Symbol: FOXH1
FOXH1
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD

Entrez Id: 91147
Gene Symbol: TMEM67
TMEM67
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD

Entrez Id: 80184
Gene Symbol: CEP290
CEP290
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD

Entrez Id: 27019
Gene Symbol: DNAI1
DNAI1
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD

Entrez Id: 352909
Gene Symbol: DNAAF3
DNAAF3
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD

Entrez Id: 79363
Gene Symbol: CPLANE2
CPLANE2
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD

Entrez Id: 221322
Gene Symbol: TBC1D32
TBC1D32
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD

Entrez Id: 162
Gene Symbol: AP1B1
AP1B1
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD

Entrez Id: 1954
Gene Symbol: MEGF8
MEGF8
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD

Entrez Id: 5991
Gene Symbol: RFX3
RFX3
CUI: C3178805
Disease: Heterotaxy Syndrome
Heterotaxy Syndrome 		0.200 Biomarker MGD