| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
smoothened, frizzled class receptor | 0.489 | 0.731 | 4.3E-07 |
|
disease | 0.700 | None | 0.955 | 18 | 2 | 1998 | 2019 | ||||||||
|
RAS p21 protein activator 1 | 0.481 | 0.885 | 1.00 |
|
disease | 0.610 | None | 1.000 | 1 | 0 | 2001 | 2001 | ||||||||
|
patched 1 | 0.398 | 0.885 | 1.00 |
|
disease | 0.500 | None | 0.942 | 102 | 6 | 1994 | 2020 | ||||||||
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
disease | 0.500 | None | 0.938 | 77 | 4 | 1992 | 2019 | ||||||||
|
melanocortin 1 receptor | 0.524 | 0.808 | 8.1E-11 |
|
disease | 0.500 | None | 1.000 | 20 | 4 | 1999 | 2015 | ||||||||
|
patched 2 | 0.563 | 0.692 | 3.4E-16 |
|
disease | 0.460 | None | 1.000 | 6 | 0 | 1999 | 2018 | ||||||||
|
BRCA1 associated protein 1 | 0.454 | 0.731 | 0.99 |
|
disease | 0.460 | None | 1.000 | 6 | 0 | 2015 | 2019 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 0.450 | None | 1.000 | 5 | 0 | 2009 | 2019 | ||||||||
|
SUFU negative regulator of hedgehog signaling | 0.493 | 0.769 | 1.00 |
|
disease | 0.440 | None | 0.750 | 4 | 0 | 2005 | 2018 | ||||||||
|
CLPTM1 like | 0.551 | 0.654 | 4.4E-05 |
|
disease | 0.430 | None | 1.000 | 3 | 2 | 2009 | 2015 | ||||||||
|
tyrosinase | 0.473 | 0.808 | 5.0E-32 |
|
disease | 0.420 | None | 1.000 | 2 | 1 | 2008 | 2011 | ||||||||
|
solute carrier family 45 member 2 | 0.626 | 0.538 | 1.7E-06 |
|
disease | 0.420 | None | 1.000 | 2 | 1 | 2009 | 2014 | ||||||||
|
XPA, DNA damage recognition and repair factor | 0.520 | 0.846 | 7.9E-05 |
|
disease | 0.420 | None | 1.000 | 2 | 0 | 2007 | 2018 | ||||||||
|
GLI family zinc finger 2 | 0.446 | 0.846 | 0.97 |
|
disease | 0.400 | None | 1.000 | 16 | 0 | 2000 | 2019 | ||||||||
|
interleukin 6 | 0.248 | 0.962 | 0.32 |
|
disease | 0.390 | None | 0.900 | 9 | 1 | 2001 | 2019 | ||||||||
|
X-ray repair cross complementing 3 | 0.505 | 0.769 | 1.9E-10 |
|
disease | 0.350 | None | 0.800 | 5 | 1 | 2004 | 2014 | ||||||||
|
keratin 5 | 0.512 | 0.731 | 0.64 |
|
disease | 0.350 | None | 1.000 | 5 | 1 | 2002 | 2019 | ||||||||
|
MYCN proto-oncogene, bHLH transcription factor | 0.454 | 0.808 | 0.89 |
|
disease | 0.340 | None | 1.000 | 4 | 0 | 2006 | 2019 | ||||||||
|
agouti signaling protein | 0.584 | 0.692 | 1.6E-02 |
|
disease | 0.320 | None | 1.000 | 2 | 0 | 2008 | 2009 | ||||||||
|
telomerase reverse transcriptase | 0.374 | 0.846 | 0.99 |
|
disease | 0.320 | None | 1.000 | 2 | 0 | 2009 | 2015 | ||||||||
|
large tumor suppressor kinase 1 | 0.563 | 0.731 | 1.00 |
|
disease | 0.320 | None | 1.000 | 2 | 0 | 2015 | 2016 | ||||||||
|
actin related protein T1 | 0.711 | 0.308 | 3.7E-03 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2017 | 2019 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2016 | 2019 | ||||||||
|
protein tyrosine phosphatase non-receptor type 14 | 0.638 | 0.615 | 0.22 |
|
disease | 0.310 | None | 1.000 | 1 | 0 | 2016 | 2016 | ||||||||
|
ERCC excision repair 2, TFIIH core complex helicase subunit | 0.420 | 0.846 | 7.1E-20 |
|
disease | 0.170 | None | 0.857 | 7 | 2 | 1999 | 2014 |