Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0017638
Disease: Glioma
Glioma
0.300 Biomarker RGD In vivo, parvovirus H-1 infection of rat glioma cells intracranially implanted into recipient animals triggers cathepsin B activation as well. 17287256

2007

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.230 Biomarker RGD Pretreatment with a combination of quercetin and alpha-tocopherol ameliorates adenosine triphosphatases and lysosomal enzymes in myocardial infarcted rats. 19958779

2010

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.230 Biomarker RGD Effect of vitamin E and human placenta cysteine peptidase inhibitor on expression of cathepsins B and L in implanted hepatoma Morris 5123 tumor model in Wistar rats. 15641152

2005

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0007766
Disease: Intracranial Aneurysm
Intracranial Aneurysm
0.210 Biomarker RGD Cathepsin B, K, and S are expressed in cerebral aneurysms and promote the progression of cerebral aneurysms. 18635848

2008

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0015695
Disease: Fatty Liver
Fatty Liver
0.210 Biomarker RGD Prevention of free fatty acid-induced hepatic lipotoxicity by 18beta-glycyrrhetinic acid through lysosomal and mitochondrial pathways. 18452148

2008

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.210 Biomarker RGD Effect of vitamin E and human placenta cysteine peptidase inhibitor on expression of cathepsins B and L in implanted hepatoma Morris 5123 tumor model in Wistar rats. 15641152

2005

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.210 Biomarker RGD Effect of vitamin E and human placenta cysteine peptidase inhibitor on expression of cathepsins B and L in implanted hepatoma Morris 5123 tumor model in Wistar rats. 15641152

2005

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0751955
Disease: Brain Infarction
Brain Infarction
0.200 Biomarker RGD Endostatin expression in neurons during the early stage of cerebral ischemia is associated with neuronal apoptotic cell death in adult hypertensive rat model of stroke. 19941836

2010

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0001925
Disease: Albuminuria
Albuminuria
0.200 Biomarker RGD Hypertension-mediated albuminuria is associated with reduced lysosomal activity in the kidney and the heart. 19023196

2009

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD The protective effect of dexanabinol (HU-211) on nitric oxide and cysteine protease-mediated neuronal death in focal cerebral ischemia. 18404379

2008

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0015652
Disease: Fascioliasis
Fascioliasis
0.200 Biomarker RGD Oxidative Modifications of Rat Liver Cell Components During Fasciola hepatica Infection. 19696938

2008

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
0.200 Biomarker RGD Prevention of free fatty acid-induced hepatic lipotoxicity by 18beta-glycyrrhetinic acid through lysosomal and mitochondrial pathways. 18452148

2008

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury
0.200 Biomarker RGD Multiple apoptogenic proteins are involved in the nuclear translocation of Apoptosis Inducing Factor during transient focal cerebral ischemia in rat. 18938146

2008

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0546127
Disease: Mercury Poisoning, Nervous System
Mercury Poisoning, Nervous System
0.200 Biomarker RGD Possible involvement of cathepsin B released by microglia in methylmercury-induced cerebellar pathological changes in the adult rat. 18638529

2008

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic
0.200 Biomarker RGD Lysosomal leakage and lack of adaptation of hepatoprotective enzyme contribute to enhanced susceptibility to ethanol-induced liver injury in female rats. 17850215

2007

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0267941
Disease: Pancreatitis, Acute Necrotizing
Pancreatitis, Acute Necrotizing
0.200 Biomarker RGD Enterokinase induces severe necrosis and rapid mortality in cerulein pancreatitis: characterization of a novel noninvasive rat model of necro-hemorrhagic pancreatitis. 17723883

2007

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma
0.200 Biomarker RGD Cytosolic activation of cathepsins mediates parvovirus H-1-induced killing of cisplatin and TRAIL-resistant glioma cells. 17287256

2007

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma
0.200 Biomarker RGD Effect of vitamin E and human placenta cysteine peptidase inhibitor on expression of cathepsins B and L in implanted hepatoma Morris 5123 tumor model in Wistar rats. 15641152

2005

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
Hepatoblastoma Caused By Somatic Mutation
0.200 Biomarker RGD Effect of vitamin E and human placenta cysteine peptidase inhibitor on expression of cathepsins B and L in implanted hepatoma Morris 5123 tumor model in Wistar rats. 15641152

2005

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0029882
Disease: Otitis Media
Otitis Media
0.200 Biomarker RGD Cathepsin gene expression profile in rat acute pneumococcal otitis media. 15179208

2004

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental
0.200 Biomarker RGD Decreased glomerular proteinase activity in the streptozotocin diabetic rat. 10393385

1999

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0022680
Disease: Polycystic Kidney Diseases
Polycystic Kidney Diseases
0.200 Biomarker RGD Alterations of cathepsins B, H and L in proximal tubules from polycystic kidneys of the Han:SPRD rat. 8840269

1996

Entrez Id: 1508
Gene Symbol: CTSB
CTSB
CUI: C0001126
Disease: Renal tubular acidosis
Renal tubular acidosis
0.200 Biomarker RGD Renal tubular cell protein breakdown in uninephrectomized and ammonium chloride-loaded rats. 7873730

1994