Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker RGD Superoxide dismutase, catalase, glutathione peroxidase and NADPH oxidase in lead-induced hypertension. 12472782

2003
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		0.510 Biomarker RGD Renal tissue abundance of gp91(phox) subunit of NAD(P)H oxidase was elevated in the untreated CRF group and was partially reduced in the iron dextran-treated CRF group. 15550752

2005
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.500 Biomarker RGD Atorvastatin protects against cerebral infarction via inhibition of NADPH oxidase-derived superoxide in ischemic stroke. 16766636

2006
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.500 Biomarker RGD Role of AT1 receptors and NAD(P)H oxidase in diabetes-aggravated ischemic brain injury. 15148062

2004
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.500 Biomarker RGD Mechanisms underlying endothelial dysfunction in diabetes mellitus. 11157681

2001
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.270 Biomarker RGD This is the first report showing that the expression of p22-phox and gp91-phox, essential components of NADPH oxidase, are increased in the infarcted sites after myocardial infarction. 11243862

2001
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C0038525
Disease: Subarachnoid Hemorrhage
Subarachnoid Hemorrhage 		0.240 Biomarker RGD Neuroprotective effect of hyperbaric oxygen in a rat model of subarachnoid hemorrhage. 16671452

2006
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C0038525
Disease: Subarachnoid Hemorrhage
Subarachnoid Hemorrhage 		0.240 Biomarker RGD Impairment of autoregulatory vasodilation by NAD(P)H oxidase-dependent superoxide generation during acute stage of subarachnoid hemorrhage in rat pial artery. 12142572

2002
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C0151650
Disease: Renal fibrosis
Renal fibrosis 		0.210 Therapeutic RGD We hypothesized that Nox2, the classical phagocytic NADPH oxidase, plays an important role in calcineurin inhibitor (CNI)-induced renal fibrosis. 22568654

2012
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5 		0.210 Biomarker RGD Iron and oxidative stress in renal insufficiency. 15550752

2005
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C2936380
Disease: Neointima
Neointima 		0.200 Therapeutic RGD Local arterial nanoparticle delivery of siRNA for NOX2 knockdown to prevent restenosis in an atherosclerotic rat model. 20485380

2010
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		0.200 Therapeutic RGD Oxidative stress contributes to pulmonary hypertension in the transgenic (mRen2)27 rat. 18424632

2008
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C0010481
Disease: Cushing Syndrome
Cushing Syndrome 		0.200 Biomarker RGD Calcium paradox of aldosteronism and the role of the parathyroid glands. 16373592

2006
Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C0020428
Disease: Hyperaldosteronism
Hyperaldosteronism 		0.200 Biomarker RGD Calcium paradox of aldosteronism and the role of the parathyroid glands. 16373592

2006