Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia 		0.600 Biomarker LHGDN These results suggest that the HMGCR gene may serve as a modifier gene for hypercholesterolemia in Chinese diabetic patients. 17870053

2007
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia 		0.600 AlteredExpression LHGDN The results of the present study, obtained by one-step RT-PCR assay, demonstrated that both SOD1 and the metal-free form of enzyme (Apo SOD1) inhibit HMG-CoA reductase gene expression in hepatocarcinoma HepG2 cells, in normal human fibroblasts, and in fibroblasts of subjects affected by familiar hypercholesterolemia. 15473258

2004
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.080 AlteredExpression LHGDN Pharmacogenetic study of statin therapy and cholesterol reduction. 15811249

2005
Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.010 GeneticVariation LHGDN Acute myocardial infarction and proinflammatory gene variants. 18056971

2007