Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C1833104
Disease: DIABETES MELLITUS, PERMANENT NEONATAL
DIABETES MELLITUS, PERMANENT NEONATAL 		1.000 Biomarker CTD_human

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Therapeutic CTD_human Arsenic exposure and calpain-10 polymorphisms impair the function of pancreatic beta-cells in humans: a pilot study of risk factors for T2DM. 23349674

2013
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Biomarker CTD_human Arsenic exposure and calpain-10 polymorphisms impair the function of pancreatic beta-cells in humans: a pilot study of risk factors for T2DM. 23349674

2013
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Biomarker CTD_human We hypothesised that the risk allele at the type 2 diabetes-associated missense polymorphism rs13266634 (R325W) in SLC30A8 would predict proinsulin levels in individuals at risk of type 2 diabetes and may modulate response to preventive interventions. 21779873

2011
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Therapeutic CTD_human Control of postprandial glucose levels with insulin in type 2 diabetes. 21680998

2011
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Therapeutic CTD_human We hypothesised that the risk allele at the type 2 diabetes-associated missense polymorphism rs13266634 (R325W) in SLC30A8 would predict proinsulin levels in individuals at risk of type 2 diabetes and may modulate response to preventive interventions. 21779873

2011
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Biomarker CTD_human Control of postprandial glucose levels with insulin in type 2 diabetes. 21680998

2011
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011854
Disease: Diabetes Mellitus, Insulin-Dependent
Diabetes Mellitus, Insulin-Dependent 		0.700 Therapeutic CTD_human Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. 20620209

2010
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.700 Therapeutic CTD_human The INS gene was sequenced in 285 patients with diabetes diagnosed before 2 years of age, 296 probands with maturity-onset diabetes of the young (MODY), and 463 patients with young-onset type 2 diabetes (nonobese, diagnosed <45 years). 18162506

2008
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.700 Biomarker CTD_human The INS gene was sequenced in 285 patients with diabetes diagnosed before 2 years of age, 296 probands with maturity-onset diabetes of the young (MODY), and 463 patients with young-onset type 2 diabetes (nonobese, diagnosed <45 years). 18162506

2008
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.700 Therapeutic CTD_human Insulin gene mutations as a cause of permanent neonatal diabetes. 17855560

2007
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.700 Biomarker CTD_human Insulin gene mutations as a cause of permanent neonatal diabetes. 17855560

2007
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Biomarker CTD_human Efficacy of biphasic insulin aspart in patients with type 2 diabetes. 16519038

2005
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Therapeutic CTD_human Beyond low-density lipoprotein: addressing the atherogenic lipid triad in type 2 diabetes mellitus and the metabolic syndrome. 16259526

2005
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Biomarker CTD_human Beyond low-density lipoprotein: addressing the atherogenic lipid triad in type 2 diabetes mellitus and the metabolic syndrome. 16259526

2005
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Therapeutic CTD_human Efficacy of biphasic insulin aspart in patients with type 2 diabetes. 16519038

2005
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.700 Biomarker CTD_human Chronic heart failure-related interventions after starting rosiglitazone in patients receiving insulin. 15628829

2004
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.700 Therapeutic CTD_human Chronic heart failure-related interventions after starting rosiglitazone in patients receiving insulin. 15628829

2004
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Therapeutic CTD_human Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin. 15531508

2004
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Biomarker CTD_human Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin. 15531508

2004
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Therapeutic CTD_human Evaluation of liver function in type 2 diabetic patients during clinical trials: evidence that rosiglitazone does not cause hepatic dysfunction. 11978674

2002
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Biomarker CTD_human Evaluation of liver function in type 2 diabetic patients during clinical trials: evidence that rosiglitazone does not cause hepatic dysfunction. 11978674

2002
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.700 Therapeutic CTD_human Hepatic necrosis with cholestasis induced by long-term voglibose administration. 11446671

2001
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.700 Biomarker CTD_human Hepatic necrosis with cholestasis induced by long-term voglibose administration. 11446671

2001
Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.700 Biomarker CTD_human Changes in matrix proteoglycans induced by insulin and fatty acids in hepatic cells may contribute to dyslipidemia of insulin resistance. 11522680

2001