Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0004096
Disease: Asthma
Asthma 		0.220 Biomarker RGD Glucocorticoids ameliorate antigen-induced bronchial smooth muscle hyperresponsiveness by inhibiting upregulation of RhoA in rats. 18391481

2008
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.210 Biomarker RGD Increased PDZ-RhoGEF/RhoA/Rho kinase signaling in small mesenteric arteries of angiotensin II-induced hypertensive rats. 17620967

2007
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0016059
Disease: Fibrosis
Fibrosis 		0.210 Biomarker RGD Attenuation of ventricular hypertrophy and fibrosis in rats by pitavastatin: potential role of the RhoA-extracellular signal-regulated kinase-serum response factor signalling pathway. 17184496

2006
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0014072
Disease: Experimental Autoimmune Encephalomyelitis
Experimental Autoimmune Encephalomyelitis 		0.200 ModifyingMutation RGD Lesional accumulation of RhoA(+) cells in brains of experimental autoimmune encephalomyelitis and multiple sclerosis. 17983427

2008
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.200 Biomarker RGD Anti-inflammatory effects of atorvastatin improve left ventricular function in experimental diabetic cardiomyopathy. 17589825

2007
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0017665
Disease: Membranous glomerulonephritis
Membranous glomerulonephritis 		0.200 Biomarker RGD Role of Rho-GTPases in complement-mediated glomerular epithelial cell injury. 17376765

2007
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		0.200 Biomarker RGD Endothelin-1 and serotonin are involved in activation of RhoA/Rho kinase signaling in the chronically hypoxic hypertensive rat pulmonary circulation. 18091588

2007
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.200 Biomarker RGD Atorvastatin lowers portal pressure in cirrhotic rats by inhibition of RhoA/Rho-kinase and activation of endothelial nitric oxide synthase. 17596891

2007
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0027055
Disease: Myocardial Reperfusion Injury
Myocardial Reperfusion Injury 		0.200 Biomarker RGD Cardioprotective effect of rosuvastatin in vivo is dependent on inhibition of geranylgeranyl pyrophosphate and altered RhoA membrane translocation. 17322412

2007
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0027814
Disease: Neuritis, Autoimmune, Experimental
Neuritis, Autoimmune, Experimental 		0.200 Biomarker RGD Expression of RhoA by inflammatory macrophages and T cells in rat experimental autoimmune neuritis. 17367505

2007
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy 		0.200 Biomarker RGD Re-expression of proteins involved in cytokinesis during cardiac hypertrophy. 17316608

2007
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0015923
Disease: Fetal Alcohol Syndrome
Fetal Alcohol Syndrome 		0.200 Biomarker RGD Ethanol impairs Rho GTPase signaling and differentiation of cerebellar granule neurons in a rodent model of fetal alcohol syndrome. 17109064

2006
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.200 Biomarker RGD Attenuation of ventricular hypertrophy and fibrosis in rats by pitavastatin: potential role of the RhoA-extracellular signal-regulated kinase-serum response factor signalling pathway. 17184496

2006
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		0.200 Biomarker RGD Involvement of RhoA/Rho kinase signaling in pulmonary hypertension of the fawn-hooded rat. 16322374

2006
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.200 Biomarker RGD Intrahepatic upregulation of RhoA and Rho-kinase signalling contributes to increased hepatic vascular resistance in rats with secondary biliary cirrhosis. 16492715

2006
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0028754
Disease: Obesity
Obesity 		0.200 Biomarker RGD Rho-kinase as a molecular target for insulin resistance and hypertension. 16267124

2006