Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3931
Gene Symbol: LCAT
LCAT
CUI: C0023195
Disease: Lecithin Acyltransferase Deficiency
Lecithin Acyltransferase Deficiency
1.000 Biomarker MGD Targeted disruption of the mouse lecithin:cholesterol acyltransferase (LCAT) gene. Generation of a new animal model for human LCAT deficiency. 9054454

1997

Entrez Id: 3931
Gene Symbol: LCAT
LCAT
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.220 Biomarker RGD ACAT inhibition reverses LCAT deficiency and improves plasma HDL in chronic renal failure. 15280162

2004

Entrez Id: 3931
Gene Symbol: LCAT
LCAT
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.220 Biomarker RGD ACAT inhibition reverses LCAT deficiency and improves plasma HDL in chronic renal failure. 15280162

2004

Entrez Id: 3931
Gene Symbol: LCAT
LCAT
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia
0.220 Biomarker RGD Poloxamer 407-mediated alterations in the activities of enzymes regulating lipid metabolism in rats. 12935429

2003

Entrez Id: 3931
Gene Symbol: LCAT
LCAT
CUI: C0020476
Disease: Hyperlipoproteinemias
Hyperlipoproteinemias
0.210 Biomarker RGD Poloxamer 407-mediated alterations in the activities of enzymes regulating lipid metabolism in rats. 12935429

2003

Entrez Id: 3931
Gene Symbol: LCAT
LCAT
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.200 Biomarker RGD Preventive effect of S-allyl cysteine sulfoxide (alliin) on cardiac marker enzymes and lipids in isoproterenol-induced myocardial injury. 16640830

2006