Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0020443
Disease: Hypercholesterolemia
Hypercholesterolemia 		0.540 Biomarker RGD Effect of dietary cholesterol on activity and mRNA levels of hepatic lipase in rat. 7830494

1995
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia 		0.500 Biomarker RGD Poloxamer 407-mediated alterations in the activities of enzymes regulating lipid metabolism in rats. 12935429

2003
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0020476
Disease: Hyperlipoproteinemias
Hyperlipoproteinemias 		0.500 Biomarker RGD Poloxamer 407-mediated alterations in the activities of enzymes regulating lipid metabolism in rats. 12935429

2003
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0020476
Disease: Hyperlipoproteinemias
Hyperlipoproteinemias 		0.500 Biomarker RGD Catabolism of very low density lipoproteins in experimental nephrosis. 6480830

1984
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0028754
Disease: Obesity
Obesity 		0.250 Biomarker RGD Lipoprotein lipase and cholesterol transfer activities of lean and obese Zucker rats. 11544558

2001
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.200 Biomarker RGD Glucose increases hepatic lipase expression in HepG2 liver cells through upregulation of upstream stimulatory factors 1 and 2. 18758746

2008
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0017668
Disease: Focal glomerulosclerosis
Focal glomerulosclerosis 		0.200 Biomarker RGD Protein restriction and AST-120 improve lipoprotein lipase and VLDL receptor in focal glomerulosclerosis. 14531811

2003
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism 		0.200 Biomarker RGD Decreased activity of lecithin:cholesterol acyltransferase and hepatic lipase in chronic hypothyroid rats: implications for reverse cholesterol transport. 12841343

2003
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0015938
Disease: Fetal Macrosomia
Fetal Macrosomia 		0.200 Biomarker RGD Time course of changes in serum glucose, insulin, lipids and tissue lipase activities in macrosomic offspring of rats with streptozotocin-induced diabetes. 10600655

2000
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0020639
Disease: Hypoproteinemia
Hypoproteinemia 		0.200 Biomarker RGD Estrogen effects on triglyceride metabolism in analbuminemic rats. 10844597

2000
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism 		0.200 Biomarker RGD Growth hormone restores hepatic lipase mRNA levels but the translation is impaired in hepatocytes of hypothyroid rats. 9106496

1997
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.200 Biomarker RGD Down-regulation of hepatic lipase expression in experimental nephrotic syndrome. 9186885

1997
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		0.200 Biomarker RGD Abnormalities in hepatic lipase in chronic renal failure: role of excess parathyroid hormone. 8636395

1996
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5 		0.200 Biomarker RGD Abnormalities in hepatic lipase in chronic renal failure: role of excess parathyroid hormone. 8636395

1996
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0033677
Disease: Protein-Energy Malnutrition
Protein-Energy Malnutrition 		0.200 Biomarker RGD Rat plasma VLDL composition and concentration and hepatic lipase and lipoprotein lipase activities are impaired during two types of protein malnutrition and unaffected by balanced refeeding. 7666262

1995
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.200 Biomarker RGD Lipoprotein lipase in experimental diabetic rats: beneficial effect of vanadate treatment. 1868959

1991
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0022116
Disease: Ischemia
Ischemia 		0.200 Biomarker RGD Metabolic responses to intermittent hepatic dearterialization in the rat. 1918876

1991
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0243026
Disease: Sepsis
Sepsis 		0.200 Biomarker RGD Gram-negative bacteria sepsis in the rat and tissue lipolytic activity on LCT and MCT/LCT-based commercial parenteral emulsions. 2113037

1990
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0001308
Disease: Acute and subacute liver necrosis (disorder)
Acute and subacute liver necrosis (disorder) 		0.200 Biomarker RGD Lipoprotein lipase and hepatic lipase deficiencies associated with impaired chylomicron clearance in D-(+) galactosamine hepatitis. 7078435

1982
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0019189
Disease: Hepatitis, Chronic
Hepatitis, Chronic 		0.200 Biomarker RGD Lipoprotein lipase and hepatic lipase deficiencies associated with impaired chylomicron clearance in D-(+) galactosamine hepatitis. 7078435

1982
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0020459
Disease: Hyperinsulinism
Hyperinsulinism 		0.200 Biomarker RGD Hepatic triacylglycerol lipase activities after induction of diabetes and administration of insulin or glucagon. 7047662

1982
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0149519
Disease: Chronic Persistent Hepatitis
Chronic Persistent Hepatitis 		0.200 Biomarker RGD Lipoprotein lipase and hepatic lipase deficiencies associated with impaired chylomicron clearance in D-(+) galactosamine hepatitis. 7078435

1982