Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		1.000 Biomarker LHGDN Role of overexpression of CD151 and/or c-Met in predicting prognosis of hepatocellular carcinoma. 19065669

2009
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		1.000 Biomarker LHGDN Role of hepatocyte growth factor/c-Met signaling in regulating urokinase plasminogen activator on invasiveness in human hepatocellular carcinoma: a potential therapeutic target. 17992475

2008
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		1.000 Biomarker LHGDN Prostaglandin E2 receptor EP1 transactivates EGFR/MET receptor tyrosine kinases and enhances invasiveness in human hepatocellular carcinoma cells. 16331686

2006
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		1.000 AlteredExpression LHGDN Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype. 16710476

2006
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0038356
Disease: Stomach Neoplasms
Stomach Neoplasms 		0.580 AlteredExpression LHGDN Gastrin and c-met protein expression were significantly higher in gastric tumor tissue than in IM (P<0.0001). 14719064

2004
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.400 Biomarker LHGDN Interactions between PTEN and the c-Met pathway in glioblastoma and implications for therapy. 19190120

2009
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 AlteredExpression LHGDN PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription. 19139719

2009
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 AlteredExpression LHGDN Activation of MET by gene amplification or by splice mutations deleting the juxtamembrane domain in primary resected lung cancers. 19096300

2009
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.400 GeneticVariation LHGDN Germline and somatic c-met mutations in multifocal/bilateral and sporadic papillary renal carcinomas of selected patients. 18636147

2008
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.400 Biomarker LHGDN HGF and c-MET as potential orchestrators of invasive growth in head and neck squamous cell carcinoma. 17981731

2008
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 Biomarker LHGDN Met gene copy number predicts the prognosis for completely resected non-small cell lung cancer. 19037978

2008
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 Biomarker LHGDN MET gene copy number in non-small cell lung cancer: molecular analysis in a targeted tyrosine kinase inhibitor naïve cohort. 18379349

2008
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.400 GeneticVariation LHGDN MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. 18093943

2007
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.400 AlteredExpression LHGDN c-Met activation in lung adenocarcinoma tissues: an immunohistochemical analysis. 17459054

2007
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.400 AlteredExpression LHGDN [Expression of c-erbB-2 and c-met proteins in gastric adenoma and adenocarcinoma]. 18172343

2007
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.400 AlteredExpression LHGDN Disruption of cerebral cortex MET signaling in autism spectrum disorder. 17696172

2007
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 Biomarker LHGDN Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival. 17332337

2007
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms 		0.400 AlteredExpression LHGDN MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. 17463250

2007
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.400 AlteredExpression LHGDN Inhibition of c-Met as a therapeutic strategy for esophageal adenocarcinoma. 17132227

2006
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.400 AlteredExpression LHGDN The significance of prohibitin and c-Met/hepatocyte growth factor receptor in the progression of cervical adenocarcinoma. 16426920

2006
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.400 AlteredExpression LHGDN Genomic amplification of MET with boundaries within fragile site FRA7G and upregulation of MET pathways in esophageal adenocarcinoma. 16186806

2006
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.400 AlteredExpression LHGDN Met receptor signaling: a key effector in esophageal adenocarcinoma. 17062664

2006
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.400 AlteredExpression LHGDN Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype. 16710476

2006
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.400 AlteredExpression LHGDN The HGF receptor c-Met is overexpressed in esophageal adenocarcinoma. 15720819

2005
Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.400 GeneticVariation LHGDN Hereditary papillary renal carcinoma type I. 15579033

2004