Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 429
Gene Symbol: ASCL1
ASCL1
CUI: C0206695
Disease: Carcinoma, Neuroendocrine
Carcinoma, Neuroendocrine
0.070 AlteredExpression LHGDN Immunohistochemical staining revealed that mASH1 was highly (sensitivity of 71%) and specifically (specificity of 95%) expressed in poorly differentiated neuroendocrine carcinoma. 18587321

2008

Entrez Id: 429
Gene Symbol: ASCL1
ASCL1
CUI: C0206695
Disease: Carcinoma, Neuroendocrine
Carcinoma, Neuroendocrine
0.070 AlteredExpression LHGDN Immunohistochemically, mammalian homologue of hASH1 was positive in 7 of 10 NECs but was negative in the other tumors. 15701827

2005

Entrez Id: 429
Gene Symbol: ASCL1
ASCL1
CUI: C0262584
Disease: Carcinoma, Small Cell
Carcinoma, Small Cell
0.040 Biomarker LHGDN Of 59 small cell carcinomas, 49 (83%) expressed MASH1 in nuclear staining whereas out of 59 small cell carcinomas, 43 (73%) expressed TTF-1 in nuclear staining. 18587322

2008

Entrez Id: 429
Gene Symbol: ASCL1
ASCL1
CUI: C0007129
Disease: Merkel cell carcinoma
Merkel cell carcinoma
0.030 Biomarker LHGDN MASH1 is a useful adjunct marker for differentiating small cell carcinoma of the lung from Merkel cell carcinoma. 18587322

2008

Entrez Id: 429
Gene Symbol: ASCL1
ASCL1
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.030 Biomarker LHGDN Achaete-scute homolog-1 linked to remodeling and preneoplasia of pulmonary epithelium. 17507989

2007

Entrez Id: 429
Gene Symbol: ASCL1
ASCL1
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.020 AlteredExpression LHGDN Human ASH1 expression in prostate cancer with neuroendocrine differentiation. 18311112

2008

Entrez Id: 429
Gene Symbol: ASCL1
ASCL1
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
0.010 Biomarker LHGDN The role of human achaete-scute homolog-1 in medullary thyroid cancer cells. 14668716

2003