Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
CUI: C0162871
Disease: Aortic Aneurysm, Abdominal
Aortic Aneurysm, Abdominal 		0.510 Biomarker RGD The objective of this study was to determine the significance of membrane type 1 matrix metalloproteinase (MT1-MMP) activation of MMP-2 in experimental abdominal aortic aneurysms. 15300177

2004
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.230 Biomarker RGD Upregulation of extracellular matrix metalloproteinase inducer (EMMPRIN) and gelatinases in human atherosclerosis infected with Chlamydia pneumoniae: the potential role of Chlamydia pneumoniae infection in the progression of atherosclerosis. 12526080

2002
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.210 Biomarker RGD Some MMPs were significantly elevated during the first week post-MI (MMP-13, -2, and -9) and another was not until 16 weeks post-MI (MMP-14). 10773235

2000
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
CUI: C0022116
Disease: Ischemia
Ischemia 		0.200 Biomarker RGD The role of MT1-MMP in ischemia-induced cadherin loss was confirmed by either blocking MT1-MMP activity with a neutralizing antibody or expression with shRNA constructs which protected full-length E- and N-cadherin during ischemia. 16077081

2006
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.200 Biomarker RGD Angiotensin type 1 receptor blockage improves ischemic injury following transient focal cerebral ischemia. 15963646

2005
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
CUI: C0887976
Disease: Chlamydophila Infections
Chlamydophila Infections 		0.200 Biomarker RGD Upregulation of extracellular matrix metalloproteinase inducer (EMMPRIN) and gelatinases in human atherosclerosis infected with Chlamydia pneumoniae: the potential role of Chlamydia pneumoniae infection in the progression of atherosclerosis. 12526080

2002
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
CUI: C0018801
Disease: Heart failure
Heart failure 		0.200 ModifyingMutation RGD MMP-8 and MMP-14 protein levels increased later during heart failure progression. 10773235

2000
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.200 ModifyingMutation RGD MMP-8 and MMP-14 protein levels increased later during heart failure progression. 10773235

2000
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
CUI: C1332309
Disease: Anti-Basement Membrane Glomerulonephritis
Anti-Basement Membrane Glomerulonephritis 		0.200 Biomarker RGD Macrophage-derived MT1-MMP and increased MMP-2 activity are associated with glomerular damage in crescentic glomerulonephritis. 10878552

2000
Entrez Id: 4323
Gene Symbol: MMP14
MMP14
CUI: C0017661
Disease: IGA Glomerulonephritis
IGA Glomerulonephritis 		0.200 Biomarker RGD Enhanced expression of membrane type-1 matrix metalloproteinase in mesangial proliferative glomerulonephritis. 9848780

1998