Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.600 Biomarker RGD Mechanistic study on liver tumor promoting effects of flutamide in rats. 22076107

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.600 Biomarker RGD Mechanistic study on liver tumor promoting effects of flutamide in rats. 22076107

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.600 Therapeutic RGD Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats. 22129741

2011
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.600 Therapeutic RGD Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats. 22129741

2011
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.590 Biomarker RGD Mechanistic study on liver tumor promoting effects of flutamide in rats. 22076107

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.590 Therapeutic RGD Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats. 22129741

2011
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.530 Therapeutic RGD MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach. 22641368

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0023904
Disease: Liver Neoplasms, Experimental
Liver Neoplasms, Experimental 		0.500 Biomarker RGD Increased expression of the N-myc gene during normal and neoplastic rat liver growth. 3335218

1988
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.300 Biomarker RGD Synergistic effect of malathion and estrogen on mammary gland carcinogenesis. 22614519

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.300 Therapeutic RGD Ellagic acid modulates antioxidant status, ornithine decarboxylase expression, and aberrant crypt foci progression in 1,2-dimethylhydrazine-instigated colon preneoplastic lesions in rats. 22439659

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.300 Biomarker RGD Chronic oxidative stress causes amplification and overexpression of ptprz1 protein tyrosine phosphatase to activate beta-catenin pathway. 18055543

2007
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.230 Therapeutic RGD Inhibitory effects of lupeal acetate of Cortex periplocae on N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis. 22844359

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma 		0.220 Biomarker RGD Mechanistic study on liver tumor promoting effects of flutamide in rats. 22076107

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0206624
Disease: Hepatoblastoma
Hepatoblastoma 		0.220 Therapeutic RGD Antioxidant N-acetyl-L-cysteine (NAC) supplementation reduces reactive oxygen species (ROS)-mediated hepatocellular tumor promotion of indole-3-carbinol (I3C) in rats. 22129741

2011
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.210 Biomarker RGD Effects of pulsed electromagnetic fields on bone mass and Wnt/β-catenin signaling pathway in ovariectomized rats. 22704852

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0022680
Disease: Polycystic Kidney Diseases
Polycystic Kidney Diseases 		0.210 Biomarker RGD Transgenic overexpression of Anks6(p.R823W) causes polycystic kidney disease in rats. 21119215

2010
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.200 Therapeutic RGD Epigallocatechin gallate, the major component of polyphenols in green tea, inhibits telomere attrition mediated cardiomyocyte apoptosis in cardiac hypertrophy. 22000973

2013
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0018129
Disease: Graft Rejection
Graft Rejection 		0.200 Biomarker RGD Efficacy of a phosphorodiamidate morpholino oligomer antisense compound in the inhibition of corneal transplant rejection in a rat cornea transplant model. 22149555

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		0.200 Therapeutic RGD Inhibitory effect of calcitonin gene-related peptide on hypoxia-induced rat pulmonary artery smooth muscle cells proliferation: role of ERK1/2 and p27. 22306243

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0023267
Disease: Fibroid Tumor
Fibroid Tumor 		0.200 Therapeutic RGD 1,25-dihydroxyvitamin D3 treatment shrinks uterine leiomyoma tumors in the Eker rat model. 22302692

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0028754
Disease: Obesity
Obesity 		0.200 Biomarker RGD Cannabis treatment in the obese group resulted in up-regulation of CB1, GLUT2, UCP2 and PKB, relative to the obese control group, while c-MYC levels were down-regulated, relative to the lean control group. 22421529

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0033375
Disease: Prolactinoma
Prolactinoma 		0.200 Biomarker RGD Genomic characterization of human and rat prolactinomas. 22635680

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0036982
Disease: Shock, Hemorrhagic
Shock, Hemorrhagic 		0.200 Therapeutic RGD Resveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1. 22113495

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C1739363
Disease: Prostatic Hypertrophy
Prostatic Hypertrophy 		0.200 Therapeutic RGD Mechanisms of prostate atrophy after LHRH antagonist cetrorelix injection: an experimental study in a rat model of benign prostatic hyperplasia. 22684563

2012
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C2676033
Disease: Hepatoblastoma Caused By Somatic Mutation
Hepatoblastoma Caused By Somatic Mutation 		0.200 Biomarker RGD Mechanistic study on liver tumor promoting effects of flutamide in rats. 22076107

2012