Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0029124
Disease: Optic Atrophy
Optic Atrophy 		0.400 Biomarker MGD

Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0018801
Disease: Heart failure
Heart failure 		0.220 Biomarker RGD Mitochondrial OPA1, apoptosis, and heart failure. 19493956

2009
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.220 Biomarker RGD Mitochondrial OPA1, apoptosis, and heart failure. 19493956

2009
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		0.210 Therapeutic RGD Curcumin prevents mitochondrial dynamics disturbances in early 5/6 nephrectomy: Relation to oxidative stress and mitochondrial bioenergetics. 27801955

2017
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.210 Biomarker RGD Compromised mitochondrial remodeling in compensatory hypertrophied myocardium of spontaneously hypertensive rat. 24388463

2014
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.210 Therapeutic RGD Expression of mitochondrial fusion-fission proteins during post-infarction remodeling: the effect of NHE-1 inhibition. 20886221

2011
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0028840
Disease: Ocular Hypertension
Ocular Hypertension 		0.210 Biomarker RGD Inducible nitric oxide synthase-mediated alteration of mitochondrial OPA1 expression in ocular hypertensive rats. 21220562

2011
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0035455
Disease: Rhinitis
Rhinitis 		0.200 Biomarker RGD PM 28146064

2017
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0151744
Disease: Myocardial Ischemia
Myocardial Ischemia 		0.200 Therapeutic RGD Vagal nerve stimulation improves mitochondrial dynamics via an M3 receptor/CaMKKβ/AMPK pathway in isoproterenol-induced myocardial ischaemia. 27491814

2017
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury 		0.200 Biomarker RGD Effect of ambient PM(2.5) on lung mitochondrial damage and fusion/fission gene expression in rats. 25560372

2015
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0007787
Disease: Transient Ischemic Attack
Transient Ischemic Attack 		0.200 Therapeutic RGD Exercise pretreatment promotes mitochondrial dynamic protein OPA1 expression after cerebral ischemia in rats. 24633199

2014
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0015695
Disease: Fatty Liver
Fatty Liver 		0.200 Biomarker RGD High-lard and high-fish-oil diets differ in their effects on function and dynamic behaviour of rat hepatic mitochondria. 24663492

2014
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0015696
Disease: Fatty Liver, Alcoholic
Fatty Liver, Alcoholic 		0.200 Biomarker RGD High-lard and high-fish-oil diets differ in their effects on function and dynamic behaviour of rat hepatic mitochondria. 24663492

2014
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.200 Biomarker RGD Compromised mitochondrial remodeling in compensatory hypertrophied myocardium of spontaneously hypertensive rat. 24388463

2014
Entrez Id: 4976
Gene Symbol: OPA1
OPA1
CUI: C0872084
Disease: Sarcopenia
Sarcopenia 		0.200 Biomarker RGD Adaptive plasticity of autophagic proteins to denervation in aging skeletal muscle. 23220115

2013