Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0085681
Disease: Hyperphosphatemia (disorder)
Hyperphosphatemia (disorder) 		0.700 Biomarker RGD Ferric citrate hydrate, a new phosphate binder, prevents the complications of secondary hyperparathyroidism and vascular calcification. 23548309

2013
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0020437
Disease: Hypercalcemia
Hypercalcemia 		0.600 Biomarker RGD Mapping the time-dependent effects of paricalcitol on serum calcium, phosphorus and parathyroid hormone levels in 5/6 nephrectomized uremic rats. 23261531

2013
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0020503
Disease: Hyperparathyroidism, Secondary
Hyperparathyroidism, Secondary 		0.600 Biomarker RGD New potent calcimimetics: II. Discovery of benzothiazole trisubstituted ureas. 23499504

2013
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.600 Therapeutic RGD Role of phytoestrogenic oils in alleviating osteoporosis associated with ovariectomy in rats. 23161222

2013
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0029456
Disease: Osteoporosis
Osteoporosis 		0.600 Biomarker RGD The bone-protective effect of genistein in the animal model of bilateral ovariectomy: roles of phytoestrogens and PTH/PTHR1 against post-menopausal osteoporosis. 22312238

2012
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0020503
Disease: Hyperparathyroidism, Secondary
Hyperparathyroidism, Secondary 		0.600 Biomarker RGD Cyclooxygenase 2 promotes parathyroid hyperplasia in ESRD. 21335517

2011
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0041948
Disease: Uremia
Uremia 		0.560 Biomarker RGD Submaximal suppression of parathyroid hormone ameliorates calcitriol-induced aortic calcification and remodeling and myocardial fibrosis in uremic rats. 22902873

2012
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		0.300 Biomarker RGD Two novel vitamin D receptor modulators with similar structures exhibit different hypercalcemic effects in 5/6 nephrectomized uremic rats. 23548814

2013
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0027709
Disease: Nephrocalcinosis
Nephrocalcinosis 		0.300 Biomarker RGD Continuous injection of parathyroid hormone (PTH) 1-34 induced nephrocalcinosis mainly in the proximal tubules in rats. 23344571

2013
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5 		0.300 Biomarker RGD Two novel vitamin D receptor modulators with similar structures exhibit different hypercalcemic effects in 5/6 nephrectomized uremic rats. 23548814

2013
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		0.300 Biomarker RGD Dietary phosphate binding and loading alter kidney angiotensin-converting enzyme mRNA and protein content in 5/6 nephrectomized rats. 22517117

2012
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C4048195
Disease: Autosomal dominant hypocalcemia
Autosomal dominant hypocalcemia 		0.300 Biomarker RGD Calcium deficiency reduces circulating levels of FGF23. 22581996

2012
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic 		0.300 Biomarker RGD The pathophysiology of early-stage chronic kidney disease-mineral bone disorder (CKD-MBD) and response to phosphate binders in the rat. 21826734

2011
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.270 Biomarker RGD Effect of a magnesium-based phosphate binder on medial calcification in a rat model of uremia. 23486515

2013
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0282201
Disease: Phosphate Diabetes
Phosphate Diabetes 		0.270 Biomarker RGD Sirolimus induced phosphaturia is not caused by inhibition of renal apical sodium phosphate cotransporters. 22859939

2012
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0342649
Disease: Vascular calcification
Vascular calcification 		0.270 ModifyingMutation RGD Occurrence of cardiovascular calcifications in normal, aging rats. 22634235

2012
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0348454
Disease: Other hypoparathyroidism
Other hypoparathyroidism 		0.200 Biomarker RGD Calcium deficiency reduces circulating levels of FGF23. 22581996

2012
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0428791
Disease: Aortic valve calcification
Aortic valve calcification 		0.200 ModifyingMutation RGD Occurrence of cardiovascular calcifications in normal, aging rats. 22634235

2012
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C3715128
Disease: HYPOCALCEMIA, AUTOSOMAL DOMINANT 1
HYPOCALCEMIA, AUTOSOMAL DOMINANT 1 		0.200 Biomarker RGD Calcium deficiency reduces circulating levels of FGF23. 22581996

2012
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C4552089
Disease: HYPOCALCEMIA, AUTOSOMAL DOMINANT 1, WITH BARTTER SYNDROME
HYPOCALCEMIA, AUTOSOMAL DOMINANT 1, WITH BARTTER SYNDROME 		0.200 Biomarker RGD Calcium deficiency reduces circulating levels of FGF23. 22581996

2012